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Transcriptome analysis

High AUROC can mask decision failure in sepsis transcriptomic classifiers: Preprocessing stability outweighs post hoc calibration across cohorts

Hongwei Zheng, Wenbiao Chen

EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy

Na Li, Qian Ma, [ ... ], Xinyi Li

An interpretable Hallmark pathway activity classifier for distinguishing CIN3/HSIL from invasive cervical squamous carcinoma: Development, external validation, and feature stability assessment

Mingyu Jia, Youyi Song, [ ... ], Mingzhu Ye

Integrated transcriptomic profiling implicates MAPK14/p38α as a candidate shared molecular target at the sepsis–postoperative delirium interface with computational evidence for a losartan–MAPK14 association

Wei-Jia Kong, Jing-Xian Xue, [ ... ], Jiang-Tao Deng

Systems pharmacology reveals type I interferon and myeloid-like B cell reprogramming as candidate druggable axes in antiphospholipid syndrome

Bin Sun, Yiqiao Lu, Wei Liu, Chengze Wang

Revisiting differential expression analysis: An updated six-dimensional comparative study

Jianxiong Wu, Shaoke Lu, Hui Yao, Zhaoyuan Fang

Identification of candidate macrophage-ferroptosis crosstalk genes associated with immune infiltration in myocardial infarction: A bioinformatics analysis

Guoqin Wang, Zhulin Zhang, [ ... ], Shuang Guo

Transcriptome analysis of hepatopancreas of Litopenaeus vannamei after acute exposure to Alexandrium pacificum

Fuyuan Zeng, Haiming Chen, [ ... ], Yulei Zhang

Integrated liver transcriptomic data reveal differences in aging-associated regulation between metabolic dysfunction-associated steatotic liver disease and normal liver aging

Tanchun Wang, Qin Huang, [ ... ], Fang Xie

A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Xue Hu, Yingzhuo Li, [ ... ], Jiaping Wang

Transcriptome profile of delayed mortality in patients with invasive group A Streptococcal disease

Ville Kailankangas, Shintaro Katayama, [ ... ], Jaana Vuopio

Major changes in gene expression between strains of diapausing and non-diapause spruce budworm

Karin R. L. van der Burg, Jeff Gauthier, [ ... ], Katie E. Marshall

Integrative bioinformatics analysis identifies gut microbiota-derived metabolite-associated immune candidate targets in high-risk primary biliary cholangitis

Jing Feng, Zhiyun Liu, Huanna Sun

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