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DNA

Dual targeting of EGFR signaling and microtubule dynamics enhances replication-associated cellular stress and suppresses tumor growth in gefitinib-resistant non-small cell lung cancer

Mohamed El-Tanani, Shakta Mani Satyam, Sainath Prabhakar, Yahia El-Tanani, Ebrahim Safaii, Syed Arman Rabbani, Mark Sutherland

published 08 Oct 2026

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A modular toolkit for theophylline-dependent synthetic auxotrophs via riboswitch-gated essential genes

Carlos Gonzalez-Lopez, Adrian Overly, Saahil Singh, Charlie Huang, Gabriel Lopez

published 08 Oct 2026

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Integrative methylome and transcriptome analyses identify LHX3 as an epigenetically downregulated marker with tumor suppressive properties in breast cancer

Kokab Farooq, Sheereen Gull, Zubia Farooq, Muhammad Talal Amin, Rana Salman Anjum, Muhammad Hassan Sarfraz, Ajaz Ahmad, Naveed Shahzad

published 07 Oct 2026

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Optimised fluorescence-activated nuclei sorting for epigenomic analysis of cortical cell types

Barry Chioza, Stefania Policicchio, Joe Burrage, Georgina E. T. Blake, Rosemary A. Bamford, Alice Franklin, Darren Soanes, Philippa M. Wells, Ann Babtie, Marina Flores Payan, Jonathan P. Davies, Anthony Klokkaris, Emma M. Walker, Joy N. Ismail, Paulina Urbanaviciute, Sarah J. Marzi, Eilis Hannon, Jonathan Mill, Emma L. Dempster

published 06 Oct 2026

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CfDNA methylation profiling in blood following moderate-to-severe traumatic brain injury using brain cell type–enriched signatures: A pilot study

Shih-Han Kao, Larry N. Singh, Jonathan Starr, Firas H. Kobeissy, Claudia Robertson, Spyridoula Tsetsou, John B. Williamson, Damon G. Lamb, Amy K. Wagner, Zhifeng Kou, Robert D. Welch, Jose-Miguel Yamal, Luis Leon-Novelo, Richard Rubenstein, Kevin K. W. Wang, Todd J. Kilbaugh

published 06 Oct 2026

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The dynamics of piRNA expression in Blattella germanica ovaries

David Pujal, Guillem Ylla, Agustina Pascual, Josep Bau, Maria-Dolors Piulachs

published 06 Oct 2026

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A lethal ORC ATPase mutation is suppressed by alterations in ORC and RNA Pol II transcription components

Luis E. Martínez-Rodríguez, Stephen P. Bell

published 30 Sep 2026

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Analysis of urinary kidney-specific cell-free DNA in preeclampsia

Vanessa C. Heron, John B. Whitlam, David H. Murray, Nicky Boulter, Peter Mount, Suet-Wan Choy, Marina Katerelos, Kathy Paizis

published 29 Sep 2026

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Waterpipe smoke condensate activates autophagy in non-tumorigenic lung epithelial cells: Implications for inflammation and stemness

Rania F. Zaarour, Bilal Azakir, Ayda S. Mahmood, Zohra Nizami, Husam Nawafleh, Yehya ElSayed, Salem Chouaib

published 24 Sep 2026

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A rapid and cost-effective Chelex-100 resin-based method for genomic DNA extraction from adult zebrafish tissues

Wei Feng, Boya Li, Yiqiong Niu, Qiannan Xu, Xiandun Zhai

published 18 Sep 2026

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Mitochondrial genome-derived microsatellites reveal genetic diversity and population structure in Callery pear populations

Alina Pokhrel, Denita Hadziabdic, Robert N. Trigiano, William E. Klingeman, David R. Coyle, Marcin Nowicki

published 17 Sep 2026

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Patient-specific integration of RNA expression, methylation-derived replication-timing proxies, and histomorphology for pancreatic cancer subtyping

Alejandro Leyva, M. Khalid Khan Niazi

published 15 Sep 2026

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A novel one-step multiplex PCR method (OS-MPCR) for efficient NGS library preparation in cancer

Haiyan Feng, Xiao Hu, Lei Zhang, Qi Zhang, Shuocun Wang, Bingqing Lv, Yufeng Zhang, Dong Shi, Ping Zhou

published 15 Sep 2026

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