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DNA cleavage

A programmable DNA roadblock system using dCas9 and multivalent target sites

Emily K. Matozel, Stephen Parziale, Allen C. Price

Pursuit of chlorovirus genetic transformation and CRISPR/Cas9-mediated gene editing

Eric A. Noel, Donald P. Weeks, James L. Van Etten

A single-molecule counting approach for convenient and ultrasensitive measurement of restriction digest efficiencies

Yi Zhang, Takuro Nunoura, [ ... ], Shigeru Deguchi

DNA binding activity of the proximal C-terminal domain of rat DNA topoisomerase IIβ is involved in ICRF-193-induced closed-clamp formation

Shinji Kawano, Kunpei Fujimoto, Kazushi Yasuda, Shogo Ikeda

A simple and affordable kinetic assay of nucleic acids with SYBR Gold gel staining

Danielle Guillen, Mika Schievelbein, [ ... ], Jonathan Ouellet

Optimizing sgRNA length to improve target specificity and efficiency for the GGTA1 gene using the CRISPR/Cas9 gene editing system

Anders W. Matson, Nora Hosny, [ ... ], Christopher Burlak

Epstein-Barr virus genome packaging factors accumulate in BMRF1-cores within viral replication compartments

Atsuko Sugimoto, Yoriko Yamashita, [ ... ], Tatsuya Tsurumi

Petri net–based model of the human DNA base excision repair pathway

Marcin Radom, Magdalena A. Machnicka, [ ... ], Piotr Formanowicz

Analyzing dwell times with the Generalized Method of Moments

Sadie Piatt, Allen C. Price

A study on endonuclease BspD6I and its stimulus-responsive switching by modified oligonucleotides

Liudmila A. Abrosimova, Anzhela Yu. Migur, [ ... ], Tatiana S. Oretskaya

Pre-existing technological core and roots for the CRISPR breakthrough

Christopher L. Magee, Patrick W. Kleyn, [ ... ], Subarna Basnet

Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

Nachiappan Dhatchana Moorthy, Bose Muthu Ramalingam, [ ... ], Elangovan Vellaichamy

BtsCI and BseGI display sequence preference in the nucleotides flanking the recognition sequence

João Rosa, Esther Fernandez-Gonzalez, Cosimo Ducani, Björn Högberg

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