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DNA repair

Differential sensitivity of MCPH1- and BRCA2-deficient cancer cells to PARP-1 inhibition

Isobel G. Chapman, Xueqin Wu, Stephany Veuger, Paul A. Jowsey

HIF1α mediates resistance to radiation and to KRAS inhibitors in pancreatic adenocarcinoma

Kevin J. Tu, Sanjit K. Roy, Tami J. Kingsbury, Hem D. Shukla

HMGB1 reduce DNA damage by binding KU70 to activate NHEJ pathway in colorectal cancer cells after radiation

Xiuxin Liu, Yuhui Han, [ ... ], Yanchao Ma

Differential modulation of haematopoietic and oxidative injury by PARP-1 and ATR kinase inhibition in a murine model of acute irradiation

Baydaa Taher Sih

A damage-structured PDE model of stem cell hierarchies: The dual role of dedifferentiation in tissue homeostasis and aging

Louis Shuo Wang, Jiguang Yu, Zonghao Liu

Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, [ ... ], Xiang Zhang

Increased sensitivity of etoposide-treated breast cancer cells with an ATM inhibitor

Arun R. K. Kumar, Crystal Sara Shaji, [ ... ], Radha Saraswathy

Predicting the influence of homologous recombination repair deficiency genes on glioma heterogeneity and patient prognosis using multi-omics analysis and machine learning

Xin Wu, Longyuan Li, [ ... ], Zhong Wang

In silico structural analysis of Oryza sativa RAD51 reveals key interactions for nucleoprotein filament assembly and regulation

Ayesha Azeem, Syed Farhat Ali, Rana Salman Anjum

Characterization of ORF19.7608 (PPP1), a biofilm-induced gene of Candida albicans

Nmerichukwu C. Iwuchukwu, Anna Carolina Borges Pereira da Costa, [ ... ], Malcolm Whiteway

PRMT5 genetic interactions with DNA double strand break repair genes

Hunter J. Bliss, Juliana Tron, [ ... ], Ruben C. Petreaca

Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out

Danny Wilbie, Selma Eising, [ ... ], Enrico Mastrobattista

An unexpected role of CLASP1 in radiation response and S-phase regulation of head and neck cancer cells

Reinout H. de Roest, Marijke Buijze, [ ... ], Ruud H. Brakenhoff

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