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Macromolecular structure analysis

A physically inspired approach to coarse-graining transcriptomes reveals the dynamics of aging

Tao Li, Madhav Mani

Identification of interaction partners of outer inflammatory protein A: Computational and experimental insights into how Helicobacter pylori infects host cells

Sümeyye Akcelik-Deveci, Elif Kılıç, [ ... ], Sinem Oktem-Okullu

Design and antiviral assessment of a panel of fusion proteins targeting human papillomavirus type 16

Chongzhi Bai, Ruoyu Wang, [ ... ], Pengcheng Han

The oral pathogen Porphyromonas gingivalis gains tolerance to the antimicrobial peptide DGL13K by synonymous mutations in hagA

Sven-Ulrik Gorr, Ruoqiong Chen, Juan E. Abrahante, Paul B. M. Joyce

Engineered red Opto-mGluR6 Opsins, a red-shifted optogenetic excitation tool, an in vitro study

Hoda Shamsnajafabadi, Zahra-Soheila Soheili, [ ... ], Ali Kashanian

Demonstration of physicochemical and functional similarity between Stimufend (pegfilgrastim-fpgk) and Neulasta (pegfilgrastim): A comparative analytical assessment

Alison Sykes, Louise Ingram, Ulrich Kronthaler, Laurent Chevalet

Designing novel multiepitope mRNA vaccine targeting Hendra virus (HeV): An integrative approach utilizing immunoinformatics, reverse vaccinology, and molecular dynamics simulation

Ahmad Abdullah Mahdeen, Imam Hossain, [ ... ], T. M. Fazla Rabbi

Examination of yield, bacteriolytic activity and cold storage of linker deletion mutants based on endolysin S6_ORF93 derived from Staphylococcus giant bacteriophage S6

Sosuke Munetomo, Jumpei Uchiyama, [ ... ], Osamu Matsushita

Bioinformatics design of peptide binding to the human cardiac troponin I (cTnI) in biosensor development for myocardial infarction diagnosis

Muhammad Miftah Jauhar, Filasta Rachel Damairetha, [ ... ], Isa Anshori

Predictive immunoinformatics reveal promising safety and anti-onchocerciasis protective immune response profiles to vaccine candidates (Ov-RAL-2 and Ov-103) in anticipation of phase I clinical trials

Derrick Neba Nebangwa, Robert Adamu Shey, [ ... ], Stephen Mbigha Ghogomu

The N-terminal activation function AF-1 domain of ERα interacts directly with the C-terminal AF-2-holding ligand-binding domain to recruit the coactivator proteins

Xiaohui Liu, Yutaka Matsuyama, [ ... ], Yasuyuki Shimohigashi

Combining metabolomics and machine learning to discover biomarkers for early-stage breast cancer diagnosis

Nguyen Ky Anh, Anbok Lee, [ ... ], Nguyen Phuoc Long

Elucidating the role of MLL1 nsSNPs: Structural and functional alterations and their contribution to leukemia development

Hakeemah H. Al-nakhle, Hind S. Yagoub, [ ... ], Ghaidaa S. Alsharif

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