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Macromolecular structure analysis

Computational structural studies of SGLT2-related polypharmacy

Aled Lloyd, Karl Austin-Muttitt, Jonathan G.L. Mullins

PRMT5 genetic interactions with DNA double strand break repair genes

Hunter J. Bliss, Juliana Tron, [ ... ], Ruben C. Petreaca

Lipid droplet distribution quantification method based on lipid droplet detection by constrained reinforcement learning

Yoshitomi Harada, Haruto Nishida, Keiko Matsuura

Cleavage of MALAT1 RNA by 14-nt sgRNA-guided tRNase Z^L

Masayuki Takahashi, Masayuki Nashimoto

Transcriptomic analysis implicates the involvement of RBM20 in Fuchs’ endothelial corneal dystrophy with TCF4 repeat expansion

Xunzhi Zhang, Ze Yu, [ ... ], Chao Xing

Identifying novel genetic variants in epidermolysis Bullosa among Middle Eastern Arab Families: Insights from whole exome sequencing and computational analysis

Nancy Shehata, Babajan Banaganapalli, [ ... ], Fahad Hakami

Traumatic brain injury reprograms lipid droplet metabolism shaped by aging and diet in Drosophila brain

Stacey A. Rimkus, Barry Ganetzky, David A. Wassarman

The type III secretion system translocases IpaC, SipC, and BipC are partially folded alpha helical proteins lacking in tertiary structures

Jacob M. Kroh, Amritangshu Chakravarty, Supratim Dey, Roberto N. De Guzman

Using systems biology and drug repositioning approaches to discover FDA-approved drugs candidates for endometriosis treatment

Samira Sanami, Shahrzad Aghaamoo, [ ... ], Mojgan Rahmanian

Integrative network toxicology and molecular docking reveal 4-Nonylphenol’s multifaceted mechanisms in breast cancer pathogenesis

Congli Jia, Fu Yang

Identification of silibinin and isotretinoin as potent up-regulators of sFRP4 (Wnt antagonist): In silico prediction and in vitro validation in breast cancer

Rehana Ramzan, Shazia Anwer Bukhari, Azhar Rasul

Circulating metabolites in patients with chronic heart failure are not related to gut leakage or gut dysbiosis

Andraž Nendl, Sajan C. Raju, [ ... ], Ayodeji Awoyemi

18 individual genes underwent variant screening in a northwest Chinese group comprised 83 probands diagnosed with early-onset high myopia

Yang Liu, Shao-Chi Zhang, [ ... ], Wen-Juan Zhuang

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