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Genome analysis

GelInsight: Open-source software for large-sample DNA fragmentation quality control in gel electrophoresis images

Kathlyne Jayne B. Bautista, Marjan Mehrab-Mohseni, Sultan A. Kiradoh, Paul A. Dayton, Samantha G. Pattenden

published 07 Jan 2026

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Manual curation for improved genome annotation of the functionally extinct northern white rhinoceros (Ceratotherium simum cottoni)

Elena Ruggeri, Julien Prunier, Marc-André Sirard, Barbara Durrant, Kristin Klohonatz

published 05 Jan 2026

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Cold plasma-induced transcriptomic reprogramming and alternative splicing in tomato plants infected with ToBRFV

Mahsa Rostami, Abozar Ghorbani, Davoud Koolivand, Abolfazl Mazandarani

published 05 Jan 2026

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A non-invasive urinary diagnostic signature for diabetic kidney disease revealed by machine learning and single-cell analysis

Yonggang Chen, Jintai Luo, Yingying Zheng, Xiaomei Jiang, Zixiang Yang, Xiaobing Liu

published 02 Jan 2026

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Genetic mapping and candidate gene identification for key physiological traits associated with heat tolerance in wheat (Triticum aestivum L.) using a MAGIC population

Ananta Bag, Hari Krishna, Vinodh Kumar P.N, Shiwani Meena, Narayana Bhat Devate, Sudhir Kumar, Ravindra Patil, Uday Govinda Reddy, Amit Kumar Singh, Badal Singh, Neelu Jain, Pradeep Kumar Singh, Gyanendra Pratap Singh

published 02 Jan 2026

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Evaluation of RNA extraction and rRNA depletion protocols for RNA-Seq in eleven edible seaweed species from brown, red, and green algae

Rob J. Dekker, Wim A. Ensink, Marina F. van Olst, Selina M. van Leeuwen, Wim C. de Leeuw, Martijs J. Jonker, Timo M. Breit

published 02 Jan 2026

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Phenome-wide screening of the putative causal determinants of bipolar affective disorder using genetic data

Bin Hu, Qi Zhou, Hao Wu, Dejiang Yang, Chongyu Xiong, Xiaowei Zhang

published 02 Jan 2026

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Next-Gen intestinal parasite detection: Leveraging metataxonomics for improved diagnosis of intestinal protists and helminths

Katherine Bedoya-Urrego, Nicolas Rozo-Montoya, Ana L. Galván-Díaz, Gisela M. Garcia-Montoya, Juan F. Alzate

published 02 Jan 2026

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Candidate orphan genes: Reassessing uniqueness

Sheetalpreet K. Maan, Xuan Y. Butzin, Steven X. Ge, Nicholas C. Butzin

published 31 Dec 2025

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Layer-specific proteomic analysis of human hearts in patients with sudden cardiac death

Yu Kakimoto, Xueting Guan, Atsushi Ueda, Yayoi Kimura, Tomoko Akiyama, Masayuki Tanaka, Haruka Ikeda, Kazuho Maeda, Shotaro Isozaki

published 30 Dec 2025

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Exploring DNA methylation profiles in blood samples of canine gastrointestinal lymphoma

Miyuki Nakamura, Yuki Matsumoto, Masatoshi Nagata, Keiji Yasuda, Kei Yonekawa, Shigeki Muramatsu, Anna Goshima, Ryo Nakaki, Nozomu Yokoyama, Ko Nakashima, Masahiro Okumura, Jumpei Yamazaki

published 30 Dec 2025

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Integrated transcriptome and metabolome analysis of melanin-related genes and metabolites in Muchuan Black Bones Chickens

Liu Wei, Jie Hong-Wei, Gao Ming-Chao, Yao Xiu-Mei, Yin Qiong, Xiang Hai, Ma Zheng, Zhang Zheng-Fen, Li Liang, Li Hua, Qi Hao, Ye Fei

published 30 Dec 2025

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Polygenic associations with clinical and neuropathological trait heterogeneity across TDP-43 proteinopathies

Barbara E. Spencer, David J. Irwin, Vivianna M. Van Deerlin, EunRan Suh, Edward B. Lee, Lauren Elman, Colin C. Quinn, Defne Amado, Michael Baer, Murray Grossman, David A. Wolk, Corey T. McMillan

published 30 Dec 2025

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