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MK-8527 is a novel inhibitor of HIV-1 reverse transcriptase translocation with potential for extended-duration dosing

Fig 10

Concentration-vs-time profiles of MK-8527 in plasma and MK-8527-TP in PBMCs following oral administration to rhesus monkeys at 50 mg/kg.

The underlying data for Fig 10 can be found in the S2 Data. PBMC, peripheral blood mononuclear cells; TP, triphosphate.

Fig 10

doi: https://doi.org/10.1371/journal.pbio.3003308.g010