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To start a submission to PLOS Biology, provide a cover letter and a PDF file containing the manuscript, figures, and supporting information files. If the editors decide that the manuscript is suitable for peer review, they will ask you to provide additional information.

This streamlined submission process allows you to quickly send your work to the journal and obtain rapid feedback from the editors without having to prepare all the materials up front. Read more about the editorial and peer review process.

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Submit a new manuscript to PLOS Biology

Author Resources

Consult these resources to make sure that your manuscript is ready for submission, and find out what to expect later on in the editorial assessment and peer review process.

Submission guidelines Information about the article types available for primary research and guidelines for manuscript style and formatting
Editorial and publishing policies Information about the requirements that apply to our submissions, including policies on data availability, competing interests, disclosure of funding sources, authorship, and reporting standards.
Other article types Information about preparing submissions to the PLOS Biology magazine.
Revision guidelines Information about preparing a revised submission.
Publication fees Information about publication fees and fee assistance options. Publication fees are US$3000 per manuscript and will be billed upon acceptance. An author’s ability to pay publication fees is never a consideration in the publication decision process.
Preprints Information about the option to post your manuscript on the bioRxiv preprint server concurrent with your submission to PLOS Biology.

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