Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease

• Rikesh M. Rajani ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: r.rajani@ucl.ac.uk (RMR); m.busche@ucl.ac.uk (MAB)

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

  https://orcid.org/0000-0003-3391-8654

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• Robert Ellingford,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• Mariam Hellmuth,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• Samuel S. Harris,

  Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• Orjona S. Taso,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• David Graykowski,

  Roles Investigation, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• Francesca Kar Wey Lam,

  Roles Investigation, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• Charles Arber,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, United Kingdom

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• Emre Fertan,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom, UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom

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• John S. H. Danial,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom, UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom, School of Physics and Astronomy, University of St Andrews, St. Andrews, United Kingdom

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• Matthew Swire,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

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• Marcus Lloyd,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

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• Tatiana A. Giovannucci,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, United Kingdom

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• Mathieu Bourdenx,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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• David Klenerman,

  Roles Supervision, Writing – review & editing

  Affiliations Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, United Kingdom, UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom

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• Robert Vassar,

  Roles Resources, Writing – review & editing

  Affiliation Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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• Selina Wray,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Department of Neurodegenerative Disease, University College London Queen Square Institute of Neurology, London, United Kingdom

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• Carlo Sala Frigerio,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

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•  [ ... ],
• Marc Aurel Busche

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: r.rajani@ucl.ac.uk (RMR); m.busche@ucl.ac.uk (MAB)

  Affiliation UK Dementia Research Institute at UCL, University College London, London, United Kingdom

  https://orcid.org/0000-0002-4416-7553

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