Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs

Noam Cohen; Hassan Massalha; Shani Ben-Moshe; Adi Egozi; Milena Rozenberg; Keren Bahar Halpern; Shalev Itzkovitz

doi:10.1371/journal.pbio.3001214

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Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs

Noam Cohen,

Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft

Affiliations Department of Biotechnology, Israel Institute for Biological Research, Ness-Ziona, Israel, Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

https://orcid.org/0000-0003-2600-6710

⨯
Hassan Massalha,

Roles Data curation

Affiliations Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom

https://orcid.org/0000-0002-9923-6878

⨯
Shani Ben-Moshe,

Roles Formal analysis

Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

https://orcid.org/0000-0002-7046-5423

⨯
Adi Egozi,

Roles Formal analysis, Software

Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
⨯
Milena Rozenberg,

Roles Data curation

Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
⨯
Keren Bahar Halpern,

Roles Data curation

Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
⨯
Shalev Itzkovitz

Roles Conceptualization, Formal analysis, Software, Supervision, Writing – original draft, Writing – review & editing

* E-mail: shalev.itzkovitz@weizmann.ac.il

Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel

https://orcid.org/0000-0003-0685-2522

⨯

Spatial gene expression maps of the intestinal lymphoid follicle and associated epithelium identify zonated expression programs

Noam Cohen,
Hassan Massalha,
Shani Ben-Moshe,
Adi Egozi,
Milena Rozenberg,
Keren Bahar Halpern,
Shalev Itzkovitz

Published: October 11, 2021
https://doi.org/10.1371/journal.pbio.3001214

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Gene expression
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Epithelium
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Gastrointestinal tract
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Peyer's patches
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Lymphoid follicles
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RNA sequencing
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Dendritic cells
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Fluorescent in situ hybridization
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