mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility

• Satoko Sakamoto ,

  Contributed equally to this work with: Satoko Sakamoto, Dean Thumkeo

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Dean Thumkeo ,

  Contributed equally to this work with: Satoko Sakamoto, Dean Thumkeo

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: d.thumkeo@mfour.med.kyoto-u.ac.jp (DT); snaru@mfour.med.kyoto-u.ac.jp (SN)

  Affiliations Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan, Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan

  http://orcid.org/0000-0002-4513-8455

  ⨯
• Hiroshi Ohta,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Anatomy and Cell Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Zhen Zhang,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Mechanobiology Institute, National University of Singapore, Singapore

  ⨯
• Shuangru Huang,

  Roles Investigation, Methodology

  Affiliation Mechanobiology Institute, National University of Singapore, Singapore

  ⨯
• Pakorn Kanchanawong,

  Roles Supervision, Writing – review & editing

  Affiliations Mechanobiology Institute, National University of Singapore, Singapore, Department of Biomedical Engineering, National University of Singapore, Singapore

  ⨯
• Takayoshi Fuu,

  Roles Investigation, Methodology

  Affiliation Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Sadanori Watanabe,

  Roles Investigation, Methodology, Writing – review & editing

  Current address: Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America

  Affiliation Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Kentaro Shimada,

  Roles Investigation, Methodology

  Affiliation Research Institute for Microbial Disease, Osaka University, Osaka, Japan

  ⨯
• Yoshitaka Fujihara,

  Roles Investigation, Methodology

  Affiliation Research Institute for Microbial Disease, Osaka University, Osaka, Japan

  ⨯
• Shosei Yoshida,

  Roles Supervision

  Affiliation National Institute for Basic Biology, Okazaki, Japan

  ⨯
• Masahito Ikawa,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Research Institute for Microbial Disease, Osaka University, Osaka, Japan

  ⨯
• Naoki Watanabe,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto, Japan, Laboratory of Single-Molecule Cell Biology, Kyoto University Graduate School of Biostudies, Kyoto, Japan

  ⨯
• Mitinori Saitou,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Anatomy and Cell Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯
• Shuh Narumiya

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: d.thumkeo@mfour.med.kyoto-u.ac.jp (DT); snaru@mfour.med.kyoto-u.ac.jp (SN)

  Affiliations Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan, Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan

  ⨯