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Open Access
Peer-reviewed
Research Article
Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1
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Shiwen Wang,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Bowen Jiang,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Tengfei Zhang,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Lixia Liu,
Affiliation Key Laboratory of Synthetic Biology, Bioinformatics Center and Laboratory of Systems Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
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Yi Wang,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Yiping Wang,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Xiufei Chen,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Huaipeng Lin,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Lisha Zhou,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Yukun Xia,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Leilei Chen,
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Chen Yang,
Affiliation Key Laboratory of Synthetic Biology, Bioinformatics Center and Laboratory of Systems Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
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Yue Xiong ,
* E-mail: yxiong@email.unc.edu (YX); yedan@fudan.edu.cn (DY); kuguan@ucsd.edu (KLG)
Affiliations Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China, Lineberger Comprehensive Cancer Center, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Dan Ye ,
* E-mail: yxiong@email.unc.edu (YX); yedan@fudan.edu.cn (DY); kuguan@ucsd.edu (KLG)
Affiliation Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China
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Kun-Liang Guan
* E-mail: yxiong@email.unc.edu (YX); yedan@fudan.edu.cn (DY); kuguan@ucsd.edu (KLG)
Affiliations Key Laboratory of Molecular Medicine of Ministry of Education and Institutes of Biomedical Sciences, Shanghai Medical College, College of Life Science, Fudan University, Shanghai, China, Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, California, United States of America
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Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1
- Shiwen Wang,
- Bowen Jiang,
- Tengfei Zhang,
- Lixia Liu,
- Yi Wang,
- Yiping Wang,
- Xiufei Chen,
- Huaipeng Lin,
- Lisha Zhou,
- Yukun Xia
- Published: September 10, 2015
- https://doi.org/10.1371/journal.pbio.1002243