Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

Zhihui Sun; Zamia Diaz; Xiaodong Fang; Michael P. Hart; Alessandra Chesi; James Shorter; Aaron D. Gitler

doi:10.1371/journal.pbio.1000614

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Peer-reviewed

Research Article

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

Zhihui Sun ,

Contributed equally to this work with: Zhihui Sun, Zamia Diaz

Affiliation Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Zamia Diaz ,

Contributed equally to this work with: Zhihui Sun, Zamia Diaz

Affiliation Department of Biochemistry and Biophysics, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Xiaodong Fang,

Affiliation Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Michael P. Hart,

Affiliation Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Alessandra Chesi,

Affiliation Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
James Shorter ,

* E-mail: gitler@mail.med.upenn.edu (ADG); jshorter@mail.med.upenn.edu (JS)

Affiliation Department of Biochemistry and Biophysics, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Aaron D. Gitler

* E-mail: gitler@mail.med.upenn.edu (ADG); jshorter@mail.med.upenn.edu (JS)

Affiliation Department of Cell and Developmental Biology, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

Zhihui Sun,
Zamia Diaz,
Xiaodong Fang,
Michael P. Hart,
Alessandra Chesi,
James Shorter,
Aaron D. Gitler

Published: April 26, 2011
https://doi.org/10.1371/journal.pbio.1000614

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