About the Authors

Izzat T. Raheem

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

izzat_raheem@merck.com (ITR); tracy_diamond@merck.com (TLD)

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Vinay Girijavallabhan

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Kerry L. Fillgrove

Roles Data curation, Formal analysis, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Shih Lin Goh

Roles Data curation, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Carolyn Bahnck-Teets

Roles Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Qian Huang

Roles Investigation, Methodology, Validation, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Fangbiao Li

Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Bang-Lin Wan

Roles Conceptualization, Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Gregory T. O’Donnell

Roles Methodology

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Jonathan B. Patteson

Roles Methodology

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Maria E. Cilento

Roles Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Amrith Bennet

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Visualization, Writing – review & editing

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Robert P. Hayes

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Visualization, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Srivanya Tummala

Roles Conceptualization, Investigation, Methodology, Writing – review & editing

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Carolyn McHale

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Judyann Wiltsie

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Joan Ellis

Roles Investigation, Methodology, Resources

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Ernest Asante-Appiah

Roles Conceptualization, Project administration, Supervision

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Daria J. Hazuda

Roles Investigation, Project administration, Resources, Supervision, Writing – review & editing

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Jeffrey Hale

Roles Conceptualization, Resources, Supervision

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Jay A. Grobler

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Min Xu

Roles Investigation, Methodology, Resources, Supervision

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Tracy L. Diamond

Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

izzat_raheem@merck.com (ITR); tracy_diamond@merck.com (TLD)

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Ming-Tain Lai

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

‡ An employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, New Jersey, United States of America, at the time the study was conducted.

Affiliation Merck & Co., Inc., Rahway, New Jersey, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: All authors are current or former employees of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, who may own stock and/or hold stock options in Merck & Co., Inc., Rahway, NJ, USA.