About the Authors

Véronique Calleja

Contributed equally to this work with: Véronique Calleja, Michel Laguerre

To whom correspondence should be addressed. E-mail: banafshe.larijani@cancer.org.uk (BL); Veronique.calleja@cancer.org.uk (VC)

Affiliation Cell Biophysics Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London, United Kingdom

Michel Laguerre

Contributed equally to this work with: Véronique Calleja, Michel Laguerre

Affiliation UMR 5248-CNRS, Institut Européen de Chimie et Biologie, Pessac, France

Peter J Parker

Affiliations Protein Phosphorylation Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London, United Kingdom , Division of Cancer Studies KCL, Guy's Hospital, London, United Kingdom

Banafshé Larijani

To whom correspondence should be addressed. E-mail: banafshe.larijani@cancer.org.uk (BL); Veronique.calleja@cancer.org.uk (VC)

Affiliation Cell Biophysics Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

VC and BL were involved in the design of the FRET experiments. VC performed the FRET experiments. VC was responsible for the design of the molecular biology tools and performed the biochemical experiments. ML was responsible for the molecular modelling. VC and BL were responsible for the set up and optimisation of two-photon FLIM. VC, ML, PJP, and BL were involved in the project strategy and in the scientific discussions. BL supervised the project. VC, ML, PJP, and BL were involved in writing the manuscript.