Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition

• Véronique Calleja ,

  Contributed equally to this work with: Véronique Calleja, Michel Laguerre

  *To whom correspondence should be addressed. E-mail: banafshe.larijani@cancer.org.uk (BL); Veronique.calleja@cancer.org.uk (VC)

  Affiliation Cell Biophysics Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London, United Kingdom

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• Michel Laguerre ,

  Contributed equally to this work with: Véronique Calleja, Michel Laguerre

  Affiliation UMR 5248-CNRS, Institut Européen de Chimie et Biologie, Pessac, France

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• Peter J Parker,

  Affiliations Protein Phosphorylation Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London, United Kingdom , Division of Cancer Studies KCL, Guy's Hospital, London, United Kingdom

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• Banafshé Larijani

  *To whom correspondence should be addressed. E-mail: banafshe.larijani@cancer.org.uk (BL); Veronique.calleja@cancer.org.uk (VC)

  Affiliation Cell Biophysics Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London, United Kingdom

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