About the Authors

Ingrid van der Pluijm

Contributed equally to this work with: Ingrid van der Pluijm, George A Garinis

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

George A Garinis

Contributed equally to this work with: Ingrid van der Pluijm, George A Garinis

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Renata M. C Brandt

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Theo G. M. F Gorgels

Current address: Department of Molecular Ophthalmology, Netherlands Ophthalmic Research Institute, Royal Netherlands Academy of Arts and Sciences, Amsterdam, Netherlands

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Susan W Wijnhoven

Affiliation National Institute of Public Health and the Environment (RIVM), Laboratory of Toxicology, Pathology and Genetics (TOX), Bilthoven, The Netherlands

Karin E. M Diderich

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Jan de Wit

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

James R Mitchell

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Conny van Oostrom

Affiliation National Institute of Public Health and the Environment (RIVM), Laboratory of Toxicology, Pathology and Genetics (TOX), Bilthoven, The Netherlands

Rudolf Beems

Affiliation National Institute of Public Health and the Environment (RIVM), Laboratory of Toxicology, Pathology and Genetics (TOX), Bilthoven, The Netherlands

Laura J Niedernhofer

Current address: University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Susana Velasco

Affiliation Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Errol C Friedberg

Affiliation Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Kiyoji Tanaka

Affiliation Division of Cellular Genetics, Institute for Molecular and Cellular Biology, Osaka University, Osaka, Japan

Harry van Steeg

Affiliation National Institute of Public Health and the Environment (RIVM), Laboratory of Toxicology, Pathology and Genetics (TOX), Bilthoven, The Netherlands

Jan H. J Hoeijmakers

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Gijsbertus T. J van der Horst

To whom correspondence should be addressed. E-mail: g.vanderhorst@erasmusmc.nl

Affiliation Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

IvdP, GAG, JHJH, and GTJvdH conceived and designed the experiments. IvdP, GAG, RMCB, TGMFG, SWW, KEMD, JdW, JRM, CvO, RB, SV, HvS, and GTJvdH performed the experiments. IvdP, GAG, and GTJvdH analyzed the data. LJN, ECF, KT, and HvS, contributed reagents/materials/analysis tools. IvdP, GAG, JHJH, and GTJvdH wrote the paper. JHJH is head of the department.