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Macromolecular structure analysis

18 individual genes underwent variant screening in a northwest Chinese group comprised 83 probands diagnosed with early-onset high myopia

Yang Liu, Shao-Chi Zhang, [ ... ], Wen-Juan Zhuang

Leveraging dynamic stability to infer regulation in protein-protein interaction networks: A study of infectious vulnerability in COPD

Joyce Reimer, Jeffrey Page, [ ... ], Gordon Broderick

Charantin targets HMGCR-PCSK9 axis and activates PPAR-α signaling to ameliorate hyperlipidemia: Mechanistic insights from bioinformatics and in-vivo studies

Ghulam Abbas, Muhammad Nasir Hayat Malik, [ ... ], Ramla Shabbir

Computational prediction of high-risk non-synonymous SNPs in human ApoE and their structural impact on amyloid-β interaction in Alzheimer’s disease pathogenesis

Md. Mainuddin Hossain, Juthi Adhikari, [ ... ], Abu Zaffar Shibly

KFERQ-selective protein autophagy in Caenorhabditis elegans depends on LMP-1

María Gallardo-Campos, Alicia N. Minniti, [ ... ], Iván E. Alfaro

Novel thiazole derivatives as effective anti-cancer agents against human osteosarcoma cell line (SaOS-2): Microwave-assisted one-pot three-component synthesis, in vitro anti-cancer studies, and in silico investigations

Arif Mermer, Aydın Tahmasebifar, [ ... ], Magdi E. A. Zaki

Evaluating the MT-CYB and MT-ATP6 variations in COVID-19 patients: A case-control study

Gazi Nurun Nahar Sultana, Md Zahid Hasan, [ ... ], Rokeya Begum

Harnessing subtractive genomics for drug target identification in Streptococcus agalactiae serotype v (atcc baa-611 / 2603 v/r) strain: An in-silico approach

Ashiqur Rahman Khan Chowdhury, Farjana Yasmin Tithi, [ ... ], Md Mahmodul Hasan Sohel

Common molecular links and therapeutic insights between type 2 diabetes and kidney cancer

Reaz Ahmmed, Mohammad Amirul Islam, [ ... ], Md. Nurul Haque Mollah

Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Cheila Rocha, Prerna Arora, [ ... ], Markus Hoffmann

Gout management: Patent analytics and computational drug design explores URAT1 inhibitors landscape

Jiaxin Zhang, Liang Hong, [ ... ], Jing Zhao

Revealing bioremediation potential of novel indigenous bacteria from oil-contaminated sites in the UAE: A combined bioinformatics and experimental validation

Sara Awni Alkhatib, Sagar Arya, [ ... ], Anna-Maria Pappa

Changes in the pulmonary surfactant in patients with mild to moderate COVID-19

Spela Kokelj, Per Larsson, [ ... ], Anna-Carin Olin

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