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Lysosomes

N-acetyl-L-leucine normalizes Transcription Factor EB activity by stereospecific bidirectional modulation in a HeLa cell model of Niemann-Pick disease type C

Lianne C. Davis, Wim Annaert, [ ... ], Antony Galione

HIV-1 Nef inhibits the JAK/STAT signaling pathway by inducing proteasomal degradation of STAT1

Roger L. Rodrigues, Mara E. da Silva-Januário, [ ... ], Luis L. P. daSilva

Human α-galactosidase A is stimulated by folic acid supplementation – possible implications in Fabry disease management

Sabiha Khatoon, Mohammed A. Junaid

LAMP2A-dependent chaperone-mediated autophagy enhances oxidative stress resistance in gastric cancer cells through selective degradation of accumulated oxidized DJ-1

Shuangshuang Le, Tongtong Guo, [ ... ], Maogui Pang

Differential regulation of p62-ubiquitin conjugates in neurons versus astrocytes during cellular stress

David K. Sidibe, Erin M. Smith, [ ... ], Sandra Maday

Metformin attenuates TBHP-induced oxidative injury in human lens epithelial cells and is associated with SIRT1/FOXO1-related autophagy

Zhuxuan Yan, Wei Chi, Zhenguo Yan, Hanrui Wang

hUMSCs-exo@Cyasterone protects the cell model of steroid-induced femur head necrosis by regulating N-glycosylation modification of CTSD-N258A

Youqiang Sun, Mengmeng Liang, [ ... ], Xiaobing Xiang

A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis

Emily Clement, Ranime Jebbawi, [ ... ], Rémy Poupot

Quantitative and temporal analysis of autophagy: Differential Response to amino acid and glucose starvation

Katie R. Martin, Stephanie L. Celano, [ ... ], Jeffrey P. MacKeigan

Auranofin, identified by FDA-approved drug library screening, inhibits HBs antigen secretion via lysosomal damage

Akiyoshi Shimoda, Kazuhiro Murai, [ ... ], Tetsuo Takehara

NLRP3 inflammasome-dependent and -independent interleukin-1β release by macrophages exposed to wear and corrosion products from CoCrMo implants

Nasteho Abdoulkader, Jennifer Archibald, [ ... ], Isabelle Catelas

Volumetric MRI of dorsal root ganglia as a biomarker for disease progression and response to AAV treatment in a mouse model of Fabry disease

Fuqiang Zhao, Shipeng Yuan, [ ... ], Talakad G. Lohith

KFERQ-selective protein autophagy in Caenorhabditis elegans depends on LMP-1

María Gallardo-Campos, Alicia N. Minniti, [ ... ], Iván E. Alfaro

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