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Lysosomes

Metformin attenuates TBHP-induced oxidative injury in human lens epithelial cells and is associated with SIRT1/FOXO1-related autophagy

Zhuxuan Yan, Wei Chi, Zhenguo Yan, Hanrui Wang

hUMSCs-exo@Cyasterone protects the cell model of steroid-induced femur head necrosis by regulating N-glycosylation modification of CTSD-N258A

Youqiang Sun, Mengmeng Liang, [ ... ], Xiaobing Xiang

A phosphorous-based dendrimer targets mitochondria and normalizes the keratinocyte proliferation/differentiation balance to improve psoriasis

Emily Clement, Ranime Jebbawi, [ ... ], Rémy Poupot

Quantitative and temporal analysis of autophagy: Differential Response to amino acid and glucose starvation

Katie R. Martin, Stephanie L. Celano, [ ... ], Jeffrey P. MacKeigan

Auranofin, identified by FDA-approved drug library screening, inhibits HBs antigen secretion via lysosomal damage

Akiyoshi Shimoda, Kazuhiro Murai, [ ... ], Tetsuo Takehara

NLRP3 inflammasome-dependent and -independent interleukin-1β release by macrophages exposed to wear and corrosion products from CoCrMo implants

Nasteho Abdoulkader, Jennifer Archibald, [ ... ], Isabelle Catelas

Volumetric MRI of dorsal root ganglia as a biomarker for disease progression and response to AAV treatment in a mouse model of Fabry disease

Fuqiang Zhao, Shipeng Yuan, [ ... ], Talakad G. Lohith

KFERQ-selective protein autophagy in Caenorhabditis elegans depends on LMP-1

María Gallardo-Campos, Alicia N. Minniti, [ ... ], Iván E. Alfaro

Identification of the Francisella novicida FTN_0096 as a factor involved in intracellular replication and host response

Dhandy Koesoemo Wardhana, Takashi Shimizu, [ ... ], Masahisa Watarai

Recombinant human alpha-N-acetylglucosamine-6-sulfatase delivered to Sanfilippo D mice with repeated intracerebroventricular injections corrects CNS pathology

Grant L. Austin, Feng Wang, [ ... ], Patricia I. Dickson

Multi-omics analysis and single-cell sequencing revealed the lysosome associated molecular subtypes and prognostic model development of papillary thyroid carcinoma

Jianhua Zhang, Kai Yue, [ ... ], Xudong Wang

Autophagy across tissues of aging mice

Julian M. Carosi, Alexis Martin, [ ... ], Timothy J. Sargeant

AAV delivery of GBA1 suppresses α-synuclein accumulation in Parkinson’s disease models and restores functions in Gaucher’s disease models

Takuro Okai, Sho Sato, [ ... ], Gabriele Proetzel

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