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Computational biology

Association of birth weight, childhood obesity, and age at menarche with the risk of ovarian dysfunction: A mendelian randomization study

Chunxiao Dang, Jianjuan Li, Xiao Yu, Jinxing Liu, Pengfei Liu, Xiaoling Yang

published 18 Jul 2024

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Trans-ancestry analysis in over 799,000 individuals yields new insights into the genetic etiology of colorectal cancer

Changlong Yang, Zhenglin Chang, Youguo Dai, Jinzhao Mo, Qitai Zhang, Mingming Zhu, Likun Luan, Jinhu Zhang, Baoqing Sun, Junyi Jia

published 18 Jul 2024

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Improving the performance of mutation-based evolving artificial neural networks with self-adaptive mutations

Motoaki Hiraga, Masahiro Komura, Akiharu Miyamoto, Daichi Morimoto, Kazuhiro Ohkura

published 15 Jul 2024

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Puzzle Hi-C: An accurate scaffolding software

Guoliang Lin, Zhiru Huang, Tingsong Yue, Jing Chai, Yan Li, Huimin Yang, Wanting Qin, Guobing Yang, Robert W. Murphy, Ya-ping Zhang, Zijie Zhang, Wei Zhou, Jing Luo

published 15 Jul 2024

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An assessment of the value of deep neural networks in genetic risk prediction for surgically relevant outcomes

Mathias Aagaard Christensen, Arnór Sigurdsson, Alexander Bonde, Simon Rasmussen, Sisse R. Ostrowski, Mads Nielsen, Martin Sillesen

published 15 Jul 2024

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Islands of cooperation emerge by stigmergic interactions in iterated spatial games

Franco Zambonelli, Federico Bergenti, Stefano Mariani, Stefania Monica

published 12 Jul 2024

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Comparative genomic analysis and optimization of astaxanthin production of Rhodotorula paludigena TL35-5 and Rhodotorula sampaioana PL61-2

Patcharaporn Hoondee, Sukanya Phuengjayaem, Engkarat Kingkaew, Pornchai Rojsitthisak, Boonchoo Sritularak, Somphob Thompho, Natapol Pornputtapong, Worathat Thitikornpong, Somboon Tanasupawat

published 12 Jul 2024

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Impact of negative emotions on upper gastrointestinal diseases: A Mendel randomization study

Nan Gao, Zhun Yu, Yu Fan, Xue Jiang, Ting Hu

published 12 Jul 2024

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The polygenic implication of clopidogrel responsiveness: Insights from platelet reactivity analysis and next-generation sequencing

Omar Echeverría, Mariana Angulo-Aguado, Ricardo Vela, Carlos Calderón-Ospina, Katherine Parra, Nora Contreras, Adrien Morel, Rodrigo Cabrera, Carlos Restrepo, Carolina Ramírez-Santana, Oscar Ortega-Recalde, Manuel Eduardo Rojas-Quintana, Luisa Murcia, Cristian Camilo Gaviria-Sabogal, Nattaly Valero, Dora Janeth Fonseca-Mendoza

published 11 Jul 2024

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In situ Patch-seq analysis of microglia reveals a lack of stress genes as found in FACS-isolated microglia

Olga Bakina, Thomas Conrad, Nina Mitic, Ramon Oliveira Vidal, Tessa Obrusnik, Somesh Sai, Christiane Nolte, Marcus Semtner, Helmut Kettenmann

published 11 Jul 2024

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Design and evaluation of antisense sequence length for modified mouse U7 small nuclear RNA to induce efficient pre-messenger RNA splicing modulation in vitro

Takenori Shimo, Otoya Ueda, Satoshi Yamamoto

published 09 Jul 2024

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Betaine and I-LG may have a predictive value for ATB: A causal study in a large European population

Xiaomin Xian, Li Li, Jing Ye, Wenxiu Mo, Dabin Liang, Minying Huang, Yue Chang, Zhezhe Cui

published 05 Jul 2024

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Transcriptional markers classifying Escherichia coli and Staphylococcus aureus induced sepsis in adults: A data-driven approach

Mahnaz Irani Shemirani

published 05 Jul 2024

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