Micro-C XL interaction heatmap of Saccharomyces cerevisiae chromosome III that visualizes differences between WT and fob1∆ strains. Red shading represents interactions higher in WT and blue represents interactions higher in the fob1∆ mutant at 10kb bin resolution. Bins containing the HML, RDT1, CEN, MAT, or HMR loci are labeled. Black arrows indicate a rightward extending line of diminishing interaction between the Fob1-anchored condensin binding site at RDT1 and the rest of chromosome III, consistent with loop extrusion activity. See Dinda et al. Download April's cover page.
Image Credit: Manikarna Dinda
Editorial
Endless microbes most beautiful and most wonderful
PLOS Genetics: published April 20, 2023 | https://doi.org/10.1371/journal.pgen.1010695
Review
Human and pathogen genotype-by-genotype interactions in the light of coevolution theory
PLOS Genetics: published April 6, 2023 | https://doi.org/10.1371/journal.pgen.1010685
Research Articles
Knockdown of the salivary protein gene NlG14 caused displacement of the lateral oviduct secreted components and inhibited ovulation in Nilaparvata lugens
PLOS Genetics: published April 3, 2023 | https://doi.org/10.1371/journal.pgen.1010704
Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage
PLOS Genetics: published April 5, 2023 | https://doi.org/10.1371/journal.pgen.1010707
The defense island repertoire of the Escherichia coli pan-genome
PLOS Genetics: published April 6, 2023 | https://doi.org/10.1371/journal.pgen.1010694
Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan
PLOS Genetics: published April 6, 2023 | https://doi.org/10.1371/journal.pgen.1010709
Heterozygous inversion breakpoints suppress meiotic crossovers by altering recombination repair outcomes
PLOS Genetics: published April 13, 2023 | https://doi.org/10.1371/journal.pgen.1010702
OsbHLH067, OsbHLH068, and OsbHLH069 redundantly regulate inflorescence axillary meristem formation in rice
PLOS Genetics: published April 13, 2023 | https://doi.org/10.1371/journal.pgen.1010698
The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans
PLOS Genetics: published April 14, 2023 | https://doi.org/10.1371/journal.pgen.1010708
Germline stem cell integrity and quiescence are controlled by an AMPK-dependent neuronal trafficking pathway
PLOS Genetics: published April 14, 2023 | https://doi.org/10.1371/journal.pgen.1010716
Fob1-dependent condensin recruitment and loop extrusion on yeast chromosome III
PLOS Genetics: published April 14, 2023 | https://doi.org/10.1371/journal.pgen.1010705
A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken
PLOS Genetics: published April 17, 2023 | https://doi.org/10.1371/journal.pgen.1010724
Insulin secretion deficits in a Prader-Willi syndrome β-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones
PLOS Genetics: published April 17, 2023 | https://doi.org/10.1371/journal.pgen.1010710
Mutations in NAKED-ENDOSPERM IDD genes reveal functional interactions with SCARECROW during leaf patterning in C4 grasses
PLOS Genetics: published April 17, 2023 | https://doi.org/10.1371/journal.pgen.1010715
Whole exome sequencing analysis of canine urothelial carcinomas without BRAF V595E mutation: Short in-frame deletions in BRAF and MAP2K1 suggest alternative mechanisms for MAPK pathway disruption
PLOS Genetics: published April 20, 2023 | https://doi.org/10.1371/journal.pgen.1010575
Bendless is essential for PINK1-Park mediated Mitofusin degradation under mitochondrial stress caused by loss of LRPPRC
PLOS Genetics: published April 25, 2023 | https://doi.org/10.1371/journal.pgen.1010493
Dynamics and stage-specificity of between-population gene expression divergence in the Drosophila melanogaster larval fat body
PLOS Genetics: published April 26, 2023 | https://doi.org/10.1371/journal.pgen.1010730
Conserved NIMA kinases regulate multiple steps of endocytic trafficking
PLOS Genetics: published April 26, 2023 | https://doi.org/10.1371/journal.pgen.1010741
A multiomic approach to defining the essential genome of the globally important pathogen Corynebacterium diphtheriae
PLOS Genetics: published April 26, 2023 | https://doi.org/10.1371/journal.pgen.1010737
Casein kinase 1 gamma regulates oxidative stress response via interacting with the NADPH dual oxidase complex
PLOS Genetics: published April 26, 2023 | https://doi.org/10.1371/journal.pgen.1010740
Imputed genomes and haplotype-based analyses of the Picts of early medieval Scotland reveal fine-scale relatedness between Iron Age, early medieval and the modern people of the UK
PLOS Genetics: published April 27, 2023 | https://doi.org/10.1371/journal.pgen.1010360
A natural single nucleotide mutation in the small regulatory RNA ArcZ of Dickeya solani switches off the antimicrobial activities against yeast and bacteria
PLOS Genetics: published April 27, 2023 | https://doi.org/10.1371/journal.pgen.1010725
Overexpression profiling reveals cellular requirements in the context of genetic backgrounds and environments
PLOS Genetics: published April 28, 2023 | https://doi.org/10.1371/journal.pgen.1010732
Corrections
Correction: Microbial phenotypic heterogeneity in response to a metabolic toxin: Continuous, dynamically shifting distribution of formaldehyde tolerance in Methylobacterium extorquens populations
PLOS Genetics: published April 5, 2023 | https://doi.org/10.1371/journal.pgen.1010714
Related Articles
Correction: Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci
PLOS Genetics: published April 18, 2023 | https://doi.org/10.1371/journal.pgen.1010735