October 2016

CERAMIC: Case-Control Association Testing in Samples with Related Individuals, Based on Retrospective Mixed Model Analysis with Adjustment for Covariates

Sheng Zhong, Duo Jiang, Mary Sara McPeek

PLOS Genetics: published October 3, 2016 | https://doi.org/10.1371/journal.pgen.1006329

Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis

Elizabeth J. Polvi, Anna F. Averette, Soo Chan Lee, Taeyup Kim, Yong-Sun Bahn, Amanda O. Veri, Nicole Robbins, Joseph Heitman, Leah E. Cowen

PLOS Genetics: published October 3, 2016 | https://doi.org/10.1371/journal.pgen.1006350

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

Martha C. Castaño-Betancourt, Dan S. Evans, Yolande F. M. Ramos, Cindy G. Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B. Kraus, Michelle S. Yau, Braxton D. Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A. Maciewicz, Nigel Arden, Rob G. H. H. Nelissen, Margreet Kloppenburg, Joanne M. Jordan, Michael C. Nevitt, Eline P. Slagboom, Deborah J. Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D. Spector, Andre G. Uitterlinden, Nancy E. Lane, Ingrid Meulenbelt, Ana M. Valdes, Joyce B. J. van Meurs

PLOS Genetics: published October 4, 2016 | https://doi.org/10.1371/journal.pgen.1006260

Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress

Simon Chang, Philane Bok, Cheng-Pu Sun, Andrew Edwards, Guo-Jen Huang

PLOS Genetics: published October 4, 2016 | https://doi.org/10.1371/journal.pgen.1006356

Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans

Vincent Portegijs, Lars-Eric Fielmich, Matilde Galli, Ruben Schmidt, Javier Muñoz, Tim van Mourik, Anna Akhmanova, Albert J. R. Heck, Mike Boxem, Sander van den Heuvel

PLOS Genetics: published October 6, 2016 | https://doi.org/10.1371/journal.pgen.1006291

MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice

Xiaolin Lin, Yujuan Qin, Junshuang Jia, Taoyan Lin, Xia Lin, Li Chen, Hui Zeng, Yanjiang Han, Lihong Wu, Shun Huang, Meng Wang, Shenhao Huang, Raoying Xie, Liqi Liang, Yu Liu, Ruiyu Liu, Tingting Zhang, Jing Li, Shengchun Wang, Penghui Sun, Wenhua Huang, Kaitai Yao, Kang Xu, Tao Du, Dong Xiao

PLOS Genetics: published October 6, 2016 | https://doi.org/10.1371/journal.pgen.1006308

A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues

Matthew Z. Anderson, Allison M. Porman, Na Wang, Eugenio Mancera, Denis Huang, Christina A. Cuomo, Richard J. Bennett

PLOS Genetics: published October 6, 2016 | https://doi.org/10.1371/journal.pgen.1006353

Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity

Miriam Kaltenbach, Stephane Emond, Florian Hollfelder, Nobuhiko Tokuriki

PLOS Genetics: published October 7, 2016 | https://doi.org/10.1371/journal.pgen.1006305

Ontogeny of Unstable Chromosomes Generated by Telomere Error in Budding Yeast

Tracey Beyer, Ted Weinert

PLOS Genetics: published October 7, 2016 | https://doi.org/10.1371/journal.pgen.1006345

Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse

Federica Federici, Aristea Magaraki, Evelyne Wassenaar, Catherina J. H. van Veen-Buurman, Christine van de Werken, Esther B Baart, Joop S. E. Laven, J Anton Grootegoed, Joost Gribnau, Willy M Baarends

PLOS Genetics: published October 7, 2016 | https://doi.org/10.1371/journal.pgen.1006358

Vimar Is a Novel Regulator of Mitochondrial Fission through Miro

Lianggong Ding, Ye Lei, Yanping Han, Yuhong Li, Xunming Ji, Lei Liu

PLOS Genetics: published October 7, 2016 | https://doi.org/10.1371/journal.pgen.1006359

Local Transcriptional Control of YUCCA Regulates Auxin Promoted Root-Growth Inhibition in Response to Aluminium Stress in Arabidopsis

Guangchao Liu, Shan Gao, Huiyu Tian, Wenwen Wu, Hélène S. Robert, Zhaojun Ding

PLOS Genetics: published October 7, 2016 | https://doi.org/10.1371/journal.pgen.1006360

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

Jian Gong, Carolyn M. Hutter, Polly A. Newcomb, Cornelia M. Ulrich, Stephanie A. Bien, Peter T. Campbell, John A. Baron, Sonja I. Berndt, Stephane Bezieau, Hermann Brenner, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Mengmeng Du, David Duggan, Jane C. Figueiredo, Steven Gallinger, Edward L. Giovannucci, Robert W. Haile, Tabitha A. Harrison, Richard B. Hayes, Michael Hoffmeister, John L. Hopper, Thomas J. Hudson, Jihyoun Jeon, Mark A. Jenkins, Jonathan Kocarnik, Sébastien Küry, Loic Le Marchand, Yi Lin, Noralane M. Lindor, Reiko Nishihara, Shuji Ogino, John D. Potter, Anja Rudolph, Robert E. Schoen, Petra Schrotz-King, Daniela Seminara, Martha L. Slattery, Stephen N. Thibodeau, Mark Thornquist, Reka Toth, Robert Wallace, Emily White, Shuo Jiao, Mathieu Lemire, Li Hsu, Ulrike Peters, CCFR and GECCO

PLOS Genetics: published October 10, 2016 | https://doi.org/10.1371/journal.pgen.1006296

High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations

Celia Payen, Anna B. Sunshine, Giang T. Ong, Jamie L. Pogachar, Wei Zhao, Maitreya J. Dunham

PLOS Genetics: published October 11, 2016 | https://doi.org/10.1371/journal.pgen.1006339

Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function

Chen-Jei Hong, Bruce A. Hamilton

PLOS Genetics: published October 11, 2016 | https://doi.org/10.1371/journal.pgen.1006357

Regulation of Dense-Core Granule Replenishment by Autocrine BMP Signalling in Drosophila Secondary Cells

Siamak Redhai, Josephine E. E. U. Hellberg, Mark Wainwright, Sumeth W. Perera, Felix Castellanos, Benjamin Kroeger, Carina Gandy, Aaron Leiblich, Laura Corrigan, Thomas Hilton, Benjamin Patel, Shih-Jung Fan, Freddie Hamdy, Deborah C. I. Goberdhan, Clive Wilson

PLOS Genetics: published October 11, 2016 | https://doi.org/10.1371/journal.pgen.1006366

Metatranscriptomic Study of Common and Host-Specific Patterns of Gene Expression between Pines and Their Symbiotic Ectomycorrhizal Fungi in the Genus Suillus

Hui-Ling Liao, Yuan Chen, Rytas Vilgalys

PLOS Genetics: published October 13, 2016 | https://doi.org/10.1371/journal.pgen.1006348

Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress

Wakana Ohashi, Shunsuke Kimura, Toshihiko Iwanaga, Yukihiro Furusawa, Tarou Irié, Hironori Izumi, Takashi Watanabe, Atsushi Hijikata, Takafumi Hara, Osamu Ohara, Haruhiko Koseki, Toshiro Sato, Sylvie Robine, Hisashi Mori, Yuichi Hattori, Hiroshi Watarai, Kenji Mishima, Hiroshi Ohno, Koji Hase, Toshiyuki Fukada

PLOS Genetics: published October 13, 2016 | https://doi.org/10.1371/journal.pgen.1006349

Dbo/Henji Modulates Synaptic dPAK to Gate Glutamate Receptor Abundance and Postsynaptic Response

Manyu Wang, Pei-Yi Chen, Chien-Hsiang Wang, Tzu-Ting Lai, Pei-I Tsai, Ying-Ju Cheng, Hsiu-Hua Kao, Cheng-Ting Chien

PLOS Genetics: published October 13, 2016 | https://doi.org/10.1371/journal.pgen.1006362

Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis

Alon Peled, Ofer Sarig, Liat Samuelov, Marta Bertolini, Limor Ziv, Daphna Weissglas-Volkov, Marina Eskin-Schwartz, Christopher A. Adase, Natalia Malchin, Ron Bochner, Gilad Fainberg, Ilan Goldberg, Koji Sugawara, Avital Baniel, Daisuke Tsuruta, Chen Luxenburg, Noam Adir, Olivier Duverger, Maria Morasso, Stavit Shalev, Richard L. Gallo, Noam Shomron, Ralf Paus, Eli Sprecher

PLOS Genetics: published October 13, 2016 | https://doi.org/10.1371/journal.pgen.1006369

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate

Weiguang Wang, Buer Song, Teni Anbarchian, Anna Shirazyan, Joshua E. Sadik, Karen M. Lyons

PLOS Genetics: published October 14, 2016 | https://doi.org/10.1371/journal.pgen.1006352

Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

Trey K. Sato, Mary Tremaine, Lucas S. Parreiras, Alexander S. Hebert, Kevin S. Myers, Alan J. Higbee, Maria Sardi, Sean J. McIlwain, Irene M. Ong, Rebecca J. Breuer, Ragothaman Avanasi Narasimhan, Mick A. McGee, Quinn Dickinson, Alex La Reau, Dan Xie, Mingyuan Tian, Jennifer L. Reed, Yaoping Zhang, Joshua J. Coon, Chris Todd Hittinger, Audrey P. Gasch, Robert Landick

PLOS Genetics: published October 14, 2016 | https://doi.org/10.1371/journal.pgen.1006372

Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp.

Zhongle Liu, Gary P. Moran, Derek J. Sullivan, Donna M. MacCallum, Lawrence C. Myers

PLOS Genetics: published October 14, 2016 | https://doi.org/10.1371/journal.pgen.1006373

Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate

Hidenori Nishihara, Naoki Kobayashi, Chiharu Kimura-Yoshida, Kuo Yan, Olga Bormuth, Qiong Ding, Akiko Nakanishi, Takeshi Sasaki, Mika Hirakawa, Kenta Sumiyama, Yasuhide Furuta, Victor Tarabykin, Isao Matsuo, Norihiro Okada

PLOS Genetics: published October 14, 2016 | https://doi.org/10.1371/journal.pgen.1006380

A New Membrane Protein Sbg1 Links the Contractile Ring Apparatus and Septum Synthesis Machinery in Fission Yeast

Kriti Sethi, Saravanan Palani, Juan C. G. Cortés, Mamiko Sato, Mayalagu Sevugan, Mariona Ramos, Shruthi Vijaykumar, Masako Osumi, Naweed I. Naqvi, Juan Carlos Ribas, Mohan Balasubramanian

PLOS Genetics: published October 17, 2016 | https://doi.org/10.1371/journal.pgen.1006383

Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining

Robin van Schendel, Jane van Heteren, Richard Welten, Marcel Tijsterman

PLOS Genetics: published October 18, 2016 | https://doi.org/10.1371/journal.pgen.1006368

Family Based Whole Exome Sequencing Reveals the Multifaceted Role of Notch Signaling in Congenital Heart Disease

Christoph Preuss, Melanie Capredon, Florian Wünnemann, Philippe Chetaille, Andrea Prince, Beatrice Godard, Severine Leclerc, Nara Sobreira, Hua Ling, Philip Awadalla, Maryse Thibeault, Paul Khairy, MIBAVA Leducq consortium, Mark E. Samuels, Gregor Andelfinger

PLOS Genetics: published October 19, 2016 | https://doi.org/10.1371/journal.pgen.1006335

Combined Use of Genome-Wide Association Data and Correlation Networks Unravels Key Regulators of Primary Metabolism in Arabidopsis thaliana

Si Wu, Saleh Alseekh, Álvaro Cuadros-Inostroza, Corina M. Fusari, Marek Mutwil, Rik Kooke, Joost B. Keurentjes, Alisdair R. Fernie, Lothar Willmitzer, Yariv Brotman

PLOS Genetics: published October 19, 2016 | https://doi.org/10.1371/journal.pgen.1006363

Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors

Emanuela Dazzo, Emanuela Leonardi, Elisa Belluzzi, Sandro Malacrida, Libero Vitiello, Elisa Greggio, Silvio C. E. Tosatto, Carlo Nobile

PLOS Genetics: published October 19, 2016 | https://doi.org/10.1371/journal.pgen.1006376

Local Adaptation of Sun-Exposure-Dependent Gene Expression Regulation in Human Skin

Ryosuke Kita, Hunter B. Fraser

PLOS Genetics: published October 19, 2016 | https://doi.org/10.1371/journal.pgen.1006382

Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein

Friederike Finsterbusch, Ramya Ravindranathan, Ihsan Dereli, Marcello Stanzione, Daniel Tränkner, Attila Tóth

PLOS Genetics: published October 19, 2016 | https://doi.org/10.1371/journal.pgen.1006393

The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana

Sarah Röhrig, Susan Schröpfer, Alexander Knoll, Holger Puchta

PLOS Genetics: published October 19, 2016 | https://doi.org/10.1371/journal.pgen.1006394

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

Johanna Jakobsdottir, Sven J. van der Lee, Joshua C. Bis, Vincent Chouraki, David Li-Kroeger, Shinya Yamamoto, Megan L. Grove, Adam Naj, Maria Vronskaya, Jose L. Salazar, Anita L. DeStefano, Jennifer A. Brody, Albert V. Smith, Najaf Amin, Rebecca Sims, Carla A. Ibrahim-Verbaas, Seung-Hoan Choi, Claudia L. Satizabal, Oscar L. Lopez, Alexa Beiser, M. Arfan Ikram, Melissa E. Garcia, Caroline Hayward, Tibor V. Varga, Samuli Ripatti, Paul W. Franks, Göran Hallmans, Olov Rolandsson, Jan-Håkon Jansson, David J. Porteous, Veikko Salomaa, Gudny Eiriksdottir, Kenneth M. Rice, Hugo J. Bellen, Daniel Levy, Andre G. Uitterlinden, Valur Emilsson, Jerome I. Rotter, Thor Aspelund, Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, Alzheimer’s Disease Genetic Consortium, Genetic and Environmental Risk in Alzheimer’s Disease consortium, Christopher J. O’Donnell, Annette L. Fitzpatrick, Lenore J. Launer, Albert Hofman, Li-San Wang, Julie Williams, Gerard D. Schellenberg, Eric Boerwinkle, Bruce M. Psaty, Sudha Seshadri, Joshua M. Shulman, Vilmundur Gudnason, Cornelia M. van Duijn

PLOS Genetics: published October 20, 2016 | https://doi.org/10.1371/journal.pgen.1006327

A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records

Thomas J. Hoffmann, Bronya J. Keats, Noriko Yoshikawa, Catherine Schaefer, Neil Risch, Lawrence R. Lustig

PLOS Genetics: published October 20, 2016 | https://doi.org/10.1371/journal.pgen.1006371

The QTL GNP1 Encodes GA20ox1, Which Increases Grain Number and Yield by Increasing Cytokinin Activity in Rice Panicle Meristems

Yuan Wu, Yun Wang, Xue-Fei Mi, Jun-Xiang Shan, Xin-Min Li, Jian-Long Xu, Hong-Xuan Lin

PLOS Genetics: published October 20, 2016 | https://doi.org/10.1371/journal.pgen.1006386

Genetic Analysis of Collective Motility of Paenibacillus sp. NAIST15-1

Kazuo Kobayashi, Yu Kanesaki, Hirofumi Yoshikawa

PLOS Genetics: published October 20, 2016 | https://doi.org/10.1371/journal.pgen.1006387

TCS1, a Microtubule-Binding Protein, Interacts with KCBP/ZWICHEL to Regulate Trichome Cell Shape in Arabidopsis thaliana

Liangliang Chen, Yuancheng Peng, Juan Tian, Xiaohong Wang, Zhaosheng Kong, Tonglin Mao, Ming Yuan, Yunhai Li

PLOS Genetics: published October 21, 2016 | https://doi.org/10.1371/journal.pgen.1006266

Multiple Pairwise Analysis of Non-homologous Centromere Coupling Reveals Preferential Chromosome Size-Dependent Interactions and a Role for Bouquet Formation in Establishing the Interaction Pattern

Philippe Lefrançois, Beth Rockmill, Pingxing Xie, G. Shirleen Roeder, Michael Snyder

PLOS Genetics: published October 21, 2016 | https://doi.org/10.1371/journal.pgen.1006347

Genetic Dissection of Aversive Associative Olfactory Learning and Memory in Drosophila Larvae

Annekathrin Widmann, Marc Artinger, Lukas Biesinger, Kathrin Boepple, Christina Peters, Jana Schlechter, Mareike Selcho, Andreas S. Thum

PLOS Genetics: published October 21, 2016 | https://doi.org/10.1371/journal.pgen.1006378

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

Christoph Nowak, Samira Salihovic, Andrea Ganna, Stefan Brandmaier, Taru Tukiainen, Corey D. Broeckling, Patrik K. Magnusson, Jessica E. Prenni, Rui Wang-Sattler, Annette Peters, Konstantin Strauch, Thomas Meitinger, Vilmantas Giedraitis, Johan Ärnlöv, Christian Berne, Christian Gieger, Samuli Ripatti, Lars Lind, Nancy L. Pedersen, Johan Sundström, Erik Ingelsson, Tove Fall

PLOS Genetics: published October 21, 2016 | https://doi.org/10.1371/journal.pgen.1006379

Dom34 Links Translation to Protein O-mannosylation

Lasse van Wijlick, René Geissen, Jessica S. Hilbig, Quentin Lagadec, Pilar D. Cantero, Eugen Pfeifer, Mateusz Juchimiuk, Sven Kluge, Stephan Wickert, Paula Alepuz, Joachim F. Ernst

PLOS Genetics: published October 21, 2016 | https://doi.org/10.1371/journal.pgen.1006395

Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq

Nicole A. Hawkins, Nicole J. Zachwieja, Alison R. Miller, Lyndsey L. Anderson, Jennifer A. Kearney

PLOS Genetics: published October 21, 2016 | https://doi.org/10.1371/journal.pgen.1006398

The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK

Cheng-Wei Wu, Andrew Deonarine, Aaron Przybysz, Kevin Strange, Keith P. Choe

PLOS Genetics: published October 24, 2016 | https://doi.org/10.1371/journal.pgen.1006361

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival

Dennis Liang Fei, Hayley Motowski, Rakesh Chatrikhi, Sameer Prasad, Jovian Yu, Shaojian Gao, Clara L. Kielkopf, Robert K. Bradley, Harold Varmus

PLOS Genetics: published October 24, 2016 | https://doi.org/10.1371/journal.pgen.1006384

The Sweet Potato NAC-Domain Transcription Factor IbNAC1 Is Dynamically Coordinated by the Activator IbbHLH3 and the Repressor IbbHLH4 to Reprogram the Defense Mechanism against Wounding

Shi-Peng Chen, Chih-Hsien Kuo, Hsueh-Han Lu, Hui-Shan Lo, Kai-Wun Yeh

PLOS Genetics: published October 25, 2016 | https://doi.org/10.1371/journal.pgen.1006397

Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance

Jonathan D. Hibshman, Anthony Hung, L. Ryan Baugh

PLOS Genetics: published October 26, 2016 | https://doi.org/10.1371/journal.pgen.1006396

Zasp52, a Core Z-disc Protein in Drosophila Indirect Flight Muscles, Interacts with α-Actinin via an Extended PDZ Domain

Kuo An Liao, Nicanor González-Morales, Frieder Schöck

PLOS Genetics: published October 26, 2016 | https://doi.org/10.1371/journal.pgen.1006400

Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice

Atsushi Fukuda, Atsushi Mitani, Toshiyuki Miyashita, Takashi Sado, Akihiro Umezawa, Hidenori Akutsu

PLOS Genetics: published October 27, 2016 | https://doi.org/10.1371/journal.pgen.1006375

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts

Natalie Saini, Steven A. Roberts, Leszek J. Klimczak, Kin Chan, Sara A. Grimm, Shuangshuang Dai, David C. Fargo, Jayne C. Boyer, William K. Kaufmann, Jack A. Taylor, Eunjung Lee, Isidro Cortes-Ciriano, Peter J. Park, Shepherd H. Schurman, Ewa P. Malc, Piotr A. Mieczkowski, Dmitry A. Gordenin

PLOS Genetics: published October 27, 2016 | https://doi.org/10.1371/journal.pgen.1006385

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues

Jinglin L. Xie, Nora Grahl, Trevor Sless, Michelle D. Leach, Sang Hu Kim, Deborah A. Hogan, Nicole Robbins, Leah E. Cowen

PLOS Genetics: published October 27, 2016 | https://doi.org/10.1371/journal.pgen.1006405

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

Emma C. Johnson, Douglas W. Bjelland, Daniel P. Howrigan, Abdel Abdellaoui, Gerome Breen, Anders Borglum, Sven Cichon, Franziska Degenhardt, Andreas J. Forstner, Josef Frank, Giulio Genovese, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffman, Wolfgang Maier, Manuel Mattheisen, Derek Morris, Bryan Mowry, Betram Müller-Mhysok, Benjamin Neale, Igor Nenadic, Markus M. Nöthen, Colm O’Dushlaine, Marcella Rietschel, Douglas M. Ruderfer, Dan Rujescu, Thomas G. Schulze, Matthew A. Simonson, Eli Stahl, Jana Strohmaier, Stephanie H. Witt, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patrick F. Sullivan, Matthew C. Keller

PLOS Genetics: published October 28, 2016 | https://doi.org/10.1371/journal.pgen.1006343

The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility

Martina Valentini, Benoît-Joseph Laventie, Joana Moscoso, Urs Jenal, Alain Filloux

PLOS Genetics: published October 28, 2016 | https://doi.org/10.1371/journal.pgen.1006354

PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance

Soto Romuald Kiando, Nathan R. Tucker, Luis-Jaime Castro-Vega, Alexander Katz, Valentina D’Escamard, Cyrielle Tréard, Daniel Fraher, Juliette Albuisson, Daniella Kadian-Dodov, Zi Ye, Erin Austin, Min-Lee Yang, Kristina Hunker, Cristina Barlassina, Daniele Cusi, Pilar Galan, Jean-Philippe Empana, Xavier Jouven, Anne-Paule Gimenez-Roqueplo, Patrick Bruneval, Esther Soo Hyun Kim, Jeffrey W. Olin, Heather L. Gornik, Michel Azizi, Pierre-François Plouin, Patrick T. Ellinor, Iftikhar J. Kullo, David J. Milan, Santhi K. Ganesh, Pierre Boutouyrie, Jason C. Kovacic, Xavier Jeunemaitre, Nabila Bouatia-Naji

PLOS Genetics: published October 28, 2016 | https://doi.org/10.1371/journal.pgen.1006367

Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis

Uddipta Biswas, Kai Hempel, Elena Llano, Alberto Pendas, Rolf Jessberger

PLOS Genetics: published October 28, 2016 | https://doi.org/10.1371/journal.pgen.1006389

Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder

Yiqin Wang, Martin Picard, Zhenglong Gu

PLOS Genetics: published October 28, 2016 | https://doi.org/10.1371/journal.pgen.1006391

Dual Role of a SAS10/C1D Family Protein in Ribosomal RNA Gene Expression and Processing Is Essential for Reproduction in Arabidopsis thaliana

Ying-Jiun C. Chen, Huei-Jing Wang, Guang-Yuh Jauh

PLOS Genetics: published October 28, 2016 | https://doi.org/10.1371/journal.pgen.1006408

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Genetics of host-specificity between pines and ectomycorrhizal fungi.

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