Ca²⁺ administration prevents α-synuclein proteotoxicity by stimulating calcineurin-dependent lysosomal proteolysis

• Lukas Habernig ,

  Contributed equally to this work with: Lukas Habernig, Filomena Broeskamp

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

  https://orcid.org/0000-0001-5649-7288

  ⨯
• Filomena Broeskamp ,

  Contributed equally to this work with: Lukas Habernig, Filomena Broeskamp

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

  ⨯
• Andreas Aufschnaiter,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Validation

  Affiliation Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden

  https://orcid.org/0000-0001-6571-2162

  ⨯
• Jutta Diessl,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

  https://orcid.org/0000-0002-4044-5413

  ⨯
• Carlotta Peselj,

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

  https://orcid.org/0000-0002-2924-7045

  ⨯
• Elisabeth Urbauer,

  Roles Data curation, Investigation, Validation

  Affiliation Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

  ⨯
• Tobias Eisenberg,

  Roles Formal analysis, Project administration, Resources, Writing – review & editing

  Affiliations Institute of Molecular Biosciences, University of Graz, Graz, Austria, BioTechMed Graz, Graz, Austria, Field of Excellence BioHealth–University of Graz, Graz, Austria

  ⨯
• Ana de Ory,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Validation, Writing – review & editing

  Affiliation Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

  ⨯
• Sabrina Büttner

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: sabrina.buettner@su.se

  Affiliations Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden, Institute of Molecular Biosciences, University of Graz, Graz, Austria

  https://orcid.org/0000-0002-2786-8542

  ⨯