-
Loading metrics
Open Access
Peer-reviewed
Research Article
A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing
-
Tao Chen ,
Contributed equally to this work with: Tao Chen, Bin Zhang, Thomas Ziegenhals, Archana B. Prusty
Roles Data curation, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing
Affiliation Laboratory for Functional Genomics and Systems Biology, Berlin Institute for Medical System Biology, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany
⨯ -
Bin Zhang ,
Contributed equally to this work with: Tao Chen, Bin Zhang, Thomas Ziegenhals, Archana B. Prusty
Roles Data curation, Methodology, Software, Writing – original draft, Writing – review & editing
Affiliations Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, China, Cancer Science Institute of Singapore, National University of Singapore, Singapore
⨯ -
Thomas Ziegenhals ,
Contributed equally to this work with: Tao Chen, Bin Zhang, Thomas Ziegenhals, Archana B. Prusty
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
Affiliation Department of Biochemistry, Theodor-Boveri-Institute, University of Würzburg, Würzburg, Germany
⨯ -
Archana B. Prusty ,
Contributed equally to this work with: Tao Chen, Bin Zhang, Thomas Ziegenhals, Archana B. Prusty
Roles Investigation, Writing – review & editing
Affiliation Department of Biochemistry, Theodor-Boveri-Institute, University of Würzburg, Würzburg, Germany
⨯ -
Sebastian Fröhler,
Roles Formal analysis
Affiliation Laboratory for Functional Genomics and Systems Biology, Berlin Institute for Medical System Biology, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany
⨯ -
Clemens Grimm,
Roles Investigation
Affiliation Department of Biochemistry, Theodor-Boveri-Institute, University of Würzburg, Würzburg, Germany
⨯ -
Yuhui Hu,
Roles Investigation
Affiliation Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, China
⨯ -
Bernhard Schaefke,
Roles Investigation
Affiliations Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, China, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology (SUSTech), Shenzhen, China
⨯ -
Liang Fang,
Roles Investigation
Affiliations Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, China, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology (SUSTech), Shenzhen, China
⨯ -
Min Zhang,
Roles Investigation, Writing – review & editing
Affiliation Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, China
⨯ -
Nadine Kraemer,
Roles Investigation
Affiliations Charité-Universitätsmedizin Berlin, Institute of Cell Biology and Neurobiology, Berlin, Germany, Charité-Universitätsmedizin Berlin, Department of Pediatric Neurology, Berlin, Germany
⨯ -
Angela M. Kaindl ,
Roles Conceptualization, Investigation, Resources
* E-mail: utz.fischer@biozentrum.uni-wuerzburg.de (UF); angela.kaindl@charite.de (AK); chenw@sustech.edu.cn (WC)
Affiliations Charité-Universitätsmedizin Berlin, Institute of Cell Biology and Neurobiology, Berlin, Germany, Charité-Universitätsmedizin Berlin, Department of Pediatric Neurology, Berlin, Germany, Charité-Universitätsmedizin Berlin, Center for Chronically Sick Children, Berlin, Germany
⨯ -
Utz Fischer ,
Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing
* E-mail: utz.fischer@biozentrum.uni-wuerzburg.de (UF); angela.kaindl@charite.de (AK); chenw@sustech.edu.cn (WC)
Affiliation Department of Biochemistry, Theodor-Boveri-Institute, University of Würzburg, Würzburg, Germany
⨯ -
Wei Chen
Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing
* E-mail: utz.fischer@biozentrum.uni-wuerzburg.de (UF); angela.kaindl@charite.de (AK); chenw@sustech.edu.cn (WC)
Affiliations Department of Biology, Southern University of Science and Technology (SUSTech), Shenzhen, China, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology (SUSTech), Shenzhen, China
⨯
A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing
- Tao Chen,
- Bin Zhang,
- Thomas Ziegenhals,
- Archana B. Prusty,
- Sebastian Fröhler,
- Clemens Grimm,
- Yuhui Hu,
- Bernhard Schaefke,
- Liang Fang,
- Min Zhang
![PLOS](/resource/img/logo-plos.png)
-
- Published: October 31, 2019
- https://doi.org/10.1371/journal.pgen.1008460