Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse

Tia DiTommaso; Lynelle K. Jones; Denny L. Cottle; The WTSI Mouse Genetics Program; Anna-Karin Gerdin; Valerie E. Vancollie; Fiona M. Watt; Ramiro Ramirez-Solis; Allan Bradley; Karen P. Steel; John P. Sundberg; Jacqueline K. White; Ian M. Smyth

doi:10.1371/journal.pgen.1004705

Loading metrics

Open Access

Peer-reviewed

Research Article

Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse

Tia DiTommaso,

Affiliation Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia
⨯
Lynelle K. Jones,

Affiliation Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia
⨯
Denny L. Cottle,

Affiliation Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia
⨯
The WTSI Mouse Genetics Program ,

¶Membership of the WTSI Mouse Genetics Program is provided in the Acknowledgments.

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Anna-Karin Gerdin,

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Valerie E. Vancollie,

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Fiona M. Watt,

Affiliation Centre for Stem Cells and Regenerative Medicine King's College London, Guy's Hospital, London, United Kingdom
⨯
Ramiro Ramirez-Solis,

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Allan Bradley,

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Karen P. Steel,

Affiliations Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom, Wolfson Centre for Age-Related Diseases, King's College London, Guy's Campus, London, United Kingdom
⨯
John P. Sundberg,

Affiliation The Jackson Laboratory, Bar Harbor, Maine, United States of America
⨯
Jacqueline K. White,

Affiliation Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Ian M. Smyth

* E-mail: ian.smyth@monash.edu

Affiliations Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, Australia, Department of Anatomy and Developmental Biology, Monash University, Clayton, Melbourne, Australia
⨯

Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse

Tia DiTommaso,
Lynelle K. Jones,
Denny L. Cottle,
The WTSI Mouse Genetics Program,
Anna-Karin Gerdin,
Valerie E. Vancollie,
Fiona M. Watt,
Ramiro Ramirez-Solis,
Allan Bradley,
Karen P. Steel

Published: October 23, 2014
https://doi.org/10.1371/journal.pgen.1004705

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Genetic screens
Is the Subject Area "Genetic screens" applicable to this article?

Thanks for your feedback.
Hair follicles
Is the Subject Area "Hair follicles" applicable to this article?

Thanks for your feedback.
Skin
Is the Subject Area "Skin" applicable to this article?

Thanks for your feedback.
Hair
Is the Subject Area "Hair" applicable to this article?

Thanks for your feedback.
Phenotypes
Is the Subject Area "Phenotypes" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Anagen phase
Is the Subject Area "Anagen phase" applicable to this article?

Thanks for your feedback.
Histopathology
Is the Subject Area "Histopathology" applicable to this article?

Thanks for your feedback.