Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4⁺ Effector Memory T Cells

• Xinli Hu ,

  Contributed equally to this work with: Xinli Hu, Hyun Kim

  Affiliations Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Harvard-MIT Division of Health Sciences and Technology, Boston, Massachusetts, United States of America

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• Hyun Kim ,

  Contributed equally to this work with: Xinli Hu, Hyun Kim

  Affiliations Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America

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• Towfique Raj,

  Affiliations Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Patrick J. Brennan,

  Affiliation Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Gosia Trynka,

  Affiliations Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Nikola Teslovich,

  Affiliations Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Kamil Slowikowski,

  Affiliations Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Wei-Min Chen,

  Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

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• Suna Onengut,

  Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

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• Clare Baecher-Allan,

  Affiliation Department of Dermatology/Harvard Skin Disease Research Center, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Philip L. De Jager,

  Affiliations Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Stephen S. Rich,

  Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

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• Barbara E. Stranger,

  Affiliations Section of Genetic Medicine, University of Chicago, Chicago, Illinois, United States of America, Institute for Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America

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• Michael B. Brenner,

  Affiliation Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Soumya Raychaudhuri

  * E-mail: soumya@broadinstitute.org

  Affiliations Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Partners Center for Personalized Genetic Medicine, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom

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