Incorporating Biological Pathways via a Markov Random Field Model in Genome-Wide Association Studies

Open Access

Peer-reviewed

Research Article

Min Chen,

Affiliation Division of Biostatistics, Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
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Judy Cho,

Affiliation Internal Medicine, Yale University, New Haven, Connecticut, United States of America
⨯
Hongyu Zhao

* E-mail: hongyu.zhao@yale.edu

Affiliation Center for Statistical Genomics and Proteomics, Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, United States of America
⨯

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Genome-wide association studies
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Crohn's disease
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Medical risk factors
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Simulation and modeling
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Markov models
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Single nucleotide polymorphisms
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Statistical distributions
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Genetics of disease
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