About the Authors

Anne Vielle

Contributed equally to this work with: Anne Vielle, Jackie Lang

Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

Jackie Lang

Contributed equally to this work with: Anne Vielle, Jackie Lang

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Yan Dong

Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

Sevinc Ercan

Affiliations Department of Biology, Carolina Center for the Genome Sciences, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America

Chitra Kotwaliwale

Affiliations Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences (QB3), University of California Berkeley, Berkeley, California, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

Andreas Rechtsteiner

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Alex Appert

Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

Q. Brent Chen

Affiliation Department of Biology, Carolina Center for the Genome Sciences, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Andrea Dose

Affiliations Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences (QB3), University of California Berkeley, Berkeley, California, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

Thea Egelhofer

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Hiroshi Kimura

Affiliation Graduate School for Frontier Biosciences, Osaka University, Osaka, Japan

Przemyslaw Stempor

Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

Abby Dernburg

Affiliations Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences (QB3), University of California Berkeley, Berkeley, California, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

Jason D. Lieb

Affiliation Department of Biology, Carolina Center for the Genome Sciences, Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Susan Strome

Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Julie Ahringer

ja219@cam.ac.uk

Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: J Ahringer, S Strome, S Ercan, C Kotwaliwale, A Dernburg, JD Lieb. Performed the experiments: A Vielle, J Lang, Y Dong, S Ercan, C Kotwaliwale, A Rechtsteiner, QB Chen, A Dose, T Egelhofer. Analyzed the data: A Vielle, J Lang, Y Dong, S Ercan, C Kotwaliwale, A Rechtsteiner, P Stempor, S Strome, J Ahringer. Contributed reagents/materials/analysis tools: H Kimura. Wrote the manuscript: J Ahringer, S Strome, S Ercan, C Kotwaliwale.