Figures
Parasitic Worm Illuminates the Memory IgE Response
A study by Adriana Turqueti-Neves, David Voehringer and colleagues reveals that repertoires of IgE—the class of antibody that mediates allergic reactions—closely resemble those of IgG1, suggesting that the memory IgE response unfolds from IgG1-switched B cells (and not from IgM-expressing B cells) in response to T cell-derived cytokines. The image shows free-living larval stages of the gastroingestinal helminth Nippostrongylus brasiliensis which was used to study the IgE response in mice. The original picture was taken with a 5x objective under a light microscope and colored using Adobe Photoshop software.
Image Credit: David Voehringer
Citation: (2015) PLoS Biology Issue Image | Vol. 13(11) November 2015. PLoS Biol 13(11): ev13.i11. https://doi.org/10.1371/image.pbio.v13.i11
Published: November 30, 2015
Copyright: © 2015 Voehringer. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A study by Adriana Turqueti-Neves, David Voehringer and colleagues reveals that repertoires of IgE—the class of antibody that mediates allergic reactions—closely resemble those of IgG1, suggesting that the memory IgE response unfolds from IgG1-switched B cells (and not from IgM-expressing B cells) in response to T cell-derived cytokines. The image shows free-living larval stages of the gastroingestinal helminth Nippostrongylus brasiliensis which was used to study the IgE response in mice. The original picture was taken with a 5x objective under a light microscope and colored using Adobe Photoshop software.
Image Credit: David Voehringer