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PLoS Biology Issue Image | Vol. 11(4) April 2013

Escape response of the nematode Caenorhabditis elegans

Complex behaviors require the temporal coordination of distinct motor programs. The escape response of the nematode C. elegans consists of a compound motor sequence in which the animal coordinates head and body movements to reverse direction and turn away from a noxious stimulus. These studies show how a monoamine neurotransmitter orchestrates different phases of the escape response through the synaptic activation of a fast-acting ion channel and extrasynaptic activation of a slow-acting G-protein coupled receptor. See Donnelly et al. in this issue.

Image Credit: Jeremy T. Florman, Christopher M. Clark, and Mark J. Alkema

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Escape response of the nematode Caenorhabditis elegans

Complex behaviors require the temporal coordination of distinct motor programs. The escape response of the nematode C. elegans consists of a compound motor sequence in which the animal coordinates head and body movements to reverse direction and turn away from a noxious stimulus. These studies show how a monoamine neurotransmitter orchestrates different phases of the escape response through the synaptic activation of a fast-acting ion channel and extrasynaptic activation of a slow-acting G-protein coupled receptor. See Donnelly et al. in this issue.

Image Credit: Jeremy T. Florman, Christopher M. Clark, and Mark J. Alkema

https://doi.org/10.1371/image.pbio.v11.i04.g001