Figures
A look through the fly eye at receptor turnover during brain wiring.
In this issue of PLoS Biology, Williamson et al., e1000553, propose that a neuron-specific protein degradation pathway is required for the spatiotemporal regulation of guidance receptors during development of the Drosophila visual system. The picture shows a preparation of the eye of the fruit fly, Drosophila melanogaster. The eye is imaged from the inside and fluorescently labeled for the light sensitive rhabdomeres using Phalloidin. A confocal maximum projection visualization was false-colored to distinguish rhabdomere cross-sections (center, blue) from tangential sections (orange). The Drosophila eye forms a stereotyped pattern during development and extends axons into the brain using specialized guidance cues.
Image Credit: Ryan Williamson and Robin Hiesinger, UT Southwestern Medical Center, United States of America
Citation: (2010) PLoS Biology Issue Image | Vol. 8(12) December 2010. PLoS Biol 8(12): ev08.i12. https://doi.org/10.1371/image.pbio.v08.i12
Published: December 21, 2010
Copyright: © 2010 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
In this issue of PLoS Biology, Williamson et al., e1000553, propose that a neuron-specific protein degradation pathway is required for the spatiotemporal regulation of guidance receptors during development of the Drosophila visual system. The picture shows a preparation of the eye of the fruit fly, Drosophila melanogaster. The eye is imaged from the inside and fluorescently labeled for the light sensitive rhabdomeres using Phalloidin. A confocal maximum projection visualization was false-colored to distinguish rhabdomere cross-sections (center, blue) from tangential sections (orange). The Drosophila eye forms a stereotyped pattern during development and extends axons into the brain using specialized guidance cues.
Image Credit: Ryan Williamson and Robin Hiesinger, UT Southwestern Medical Center, United States of America