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PLoS Biology Issue Image | Vol. 7(10) October 2009

Worker females guarding the nest entrance of a honeybee colony.

Each colony has thousands of female workers, one queen, and a few hundred males (drones). This strong sex bias relies on an unusual sex determination system. Gempe et al. (e1000222) show key functions for the regulation of two genes: csd, which establishes the decision between males and females by allelic combination, and fem, which memorizes the sexual decision by a positive regulatory feedback loop that operates throughout development.

Image Credit: Björn Schmitt, Heinrich-Heine-Universität Düsseldorf

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Worker females guarding the nest entrance of a honeybee colony.

Each colony has thousands of female workers, one queen, and a few hundred males (drones). This strong sex bias relies on an unusual sex determination system. Gempe et al. (e1000222) show key functions for the regulation of two genes: csd, which establishes the decision between males and females by allelic combination, and fem, which memorizes the sexual decision by a positive regulatory feedback loop that operates throughout development.

Image Credit: Björn Schmitt, Heinrich-Heine-Universität Düsseldorf

https://doi.org/10.1371/image.pbio.v07.i10.g001