Figures
A mouse with Cockayne syndrome.
Artist impression of the Csb/Xpa mouse model for the progeroid DNA repair disorder Cockayne syndrome. This animal model shows dwarf growth, neurological abnormalities, aging-associated pathology, and premature death. A comparison of the transcriptome of normal and mutant mouse livers revealed a novel link between genome instability and the age-related decline of the somatotroph axis (see van der Pluijm et al., e2).
Image Credit: Image by Ingrid van der Pluijm
Citation: (2007) PLoS Biology Issue Image | Vol. 5(1) January 2007. PLoS Biol 5(1): ev05.i01. https://doi.org/10.1371/image.pbio.v05.i01
Published: January 30, 2007
Copyright: © 2007 Ingrid van der Pluijm. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Artist impression of the Csb/Xpa mouse model for the progeroid DNA repair disorder Cockayne syndrome. This animal model shows dwarf growth, neurological abnormalities, aging-associated pathology, and premature death. A comparison of the transcriptome of normal and mutant mouse livers revealed a novel link between genome instability and the age-related decline of the somatotroph axis (see van der Pluijm et al., e2).
Image Credit: Image by Ingrid van der Pluijm