Figures
Arthritic limbs from mice with autoimmune disease.
A dynamic tuning process restricts the responsiveness of autoreactive T cells, but its relative inefficiency in abrogating effector functionality results in arthritis and autoantibody production (bottom panels). Singh et al. examine the separable contributions of intrinsic and extrinsic regulatory processes to the control of peripheral autoimmunity.
Image Credit: Nevil Singh
Citation: (2006) PLoS Biology Issue Image | Vol. 4(11) November 2006. PLoS Biol 4(11): ev04.i11. https://doi.org/10.1371/image.pbio.v04.i11
Published: November 28, 2006
Copyright: © 2006 Nevil Singh. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
A dynamic tuning process restricts the responsiveness of autoreactive T cells, but its relative inefficiency in abrogating effector functionality results in arthritis and autoantibody production (bottom panels). Singh et al. examine the separable contributions of intrinsic and extrinsic regulatory processes to the control of peripheral autoimmunity.
Image Credit: Nevil Singh