Figures
A cross section of abnormally thickened skin epidermis from Snail transgenic mice.
Epidermal thickening is seen in the skin of transgenic mice expressing the transcription factor Snail, as shown in this skin section. Expansion of basal and terminally differentiating layers occurs, as detected by antibodies against keratin 5 (green), which normally marks the innermost (basal) layer, and against filaggrin (red), a late-stage marker of upper layers. (See Jamora et al.)
Citation: (2005) PLoS Biology Issue Image | Vol. 3(1) January 2005. PLoS Biol 3(1): ev03.i01. https://doi.org/10.1371/image.pbio.v03.i01
Published: January 25, 2005
Copyright: © 2005 Jamora et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Epidermal thickening is seen in the skin of transgenic mice expressing the transcription factor Snail, as shown in this skin section. Expansion of basal and terminally differentiating layers occurs, as detected by antibodies against keratin 5 (green), which normally marks the innermost (basal) layer, and against filaggrin (red), a late-stage marker of upper layers. (See Jamora et al.)