Table 1.
Demographic information and behavioral test performance.
Fig 1.
Grey matter volume of the right parietal cortex of 3-6-year-old children without mathematical training is associated with the cortical growth gene ROBO1.
(A) Outer corner points depict 10 known math candidate genes and their corresponding numbered chromosomes. Dashed lines depict R2 statistics quantifying the strength of associations between the genes and the grey matter volume images. The further away a point is from the center, the stronger the association is. Orange points/lines refer to the exploration sample, and blue points/lines refer to the replication sample. (B–D) Right sagittal view on a cortical surface projection of P-value images showing the right parietal clusters that were significantly associated with ROBO1. Results are shown separately for the exploration sample (B), the replication sample (C), and the overlap between both samples (D). The color bar indicates the range of P-values with a lower threshold of P < 0.05 and an upper threshold of P < 0.01, family-wise-error-corrected for the number of voxels and genes tested. The numerical data used in this figure are included in S1 Data.
Table 2.
Genotypic information.
Fig 2.
ROBO1-associated grey matter volume of the right parietal cortex of 3–6-year-old children without mathematical training predicts mathematical ability in school at 7–9 years of age.
(A–C) Right sagittal view on a cortical surface projection of P-value images showing voxels within parietal clusters that were significantly associated with ROBO1 at 3–6 years of age and with individual scores of a mathematical ability test conducted at 7–9 years of age. Results are shown separately for the exploration sample (A), the replication sample (B), and the overlap between both samples (C). The color bar indicates the range of P-values with a lower threshold of P < 0.05 and an upper threshold of P < 0.01 (voxel-wise permutation-corrected). The numerical data used in this figure are included in S2 Data.