Layers of the monkey visual cortex are selectively modulated during electrical stimulation
Fig 5
Multi-unit activity responses across cortical layers in monkey 2.
A) Peri-stimulus time histograms (PSTHs) across layers under Flash and Flash + AC conditions, aligned to visual stimulus onset (0 ms) and extending to 250 ms. Each bar represents the firing rate (spikes/s) within a 10 ms time bin. B) Comparison of time-averaged firing rates between superficial layers (layers 2/3) and deeper layers (layers 5/6) under both conditions. Firing rates of MUA were significantly higher in layers 5/6 for both conditions (paired t test, p < 0.01), and AC significantly increased firing rates only in layers 5/6 (unpaired t test, p < 0.01). C) PSTHs across layers for trials aligned to the peak and trough phases of AC. D) Comparison of time-averaged firing rates between superficial layers and deeper layers across AC phases. No significant differences were found. Underlying data for this figure are provided in S1 Data.