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Layers of the monkey visual cortex are selectively modulated during electrical stimulation

Fig 2

Effects of electrical stimulation on layer-specific visual-evoked LFPs in V1.

A) Local field potentials (LFPs) recorded using a multisite probe for monkey 1. LFPs along contacts (0.1 mm spacing) during the Flash condition (blue line) and the Flash + AC condition (red line). LFPs were normalized relative to the last contact, which has the largest LFP, followed by averaging them across trials at each contact. Time indicates the duration from the flash visual stimulus onset. B) LFPs in layers 5/6 for both capuchin monkeys. Normalized LFPs were averaged across trials and contacts within layers 5/6. Thick lines and shades represent the averaged LFP and standard deviation, respectively. The cluster-based permutation test determined significant differences between the Flash and Flash + AC conditions across contacts in the time range from 0 to 250 ms. Significant differences occurred within the contacts in layers 4–6 after 100 ms from the onset of the flash visual stimulus. The gray shade represents time windows where significant differences were observed (**p < 0.01; n.s., not significant).

Fig 2

doi: https://doi.org/10.1371/journal.pbio.3003278.g002