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Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan

Fig 7

Data-driven mapping and functional annotation of vascular territories.

(a) The first two gradients of blood perfusion covariance matrix are shown on the inflated and 2D flat cortical surfaces (fsLR), and subcortical regions are shown on a subcortical mask (from HCP-S release). (b) The arterial territories for posterior cerebral artery, middle cerebral artery and anterior cerebral artery from an independent stroke-based atlas [142,143]. (c) Correlation values between cortical gradient maps and Neurosynth meta-analytic atlas (x-axis: correlations with gradient 1; y-axis: correlations with gradient 2). Here, only functional/cognitive terms with correlation values exceeding thresholds determined by spatial auto-correlation-preserving permutation nulls ( > 0.05) are annotated; for a list of 124 included Neurosynth functional/cognitive terms refer to S8 Table.

doi: https://doi.org/10.1371/journal.pbio.3003277.g007