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Cilia in the brain display region-dependent oscillations of length and orientation

Fig 5

Fluctuation of cilia length and cilia circular angle across 24-hours’ time.

(A and B) Diurnal fluctuations of cilia length (A) and angle (B): The plots show the means ± SE of cilia length and angle over the course of 24-h day in different brain regions. The brain regions are grouped into major categories including, the Hypothalamus, Hippocampus, Cortices, and Striatum. The average length and angle are determined based on the measurements’ means in each brain section; Zeitgeber time (ZT). One-way ANOVA test was used to compare the means of lengths and angles at different time points. P values were calculated using the False Discovery Rate (FDR) correction, employing the Two-stage linear step-up procedure of Benjamini, Krieger, and Yekutieli for multiple comparisons. (C) P values of one-way ANOVA test, used to assess the variability in cilia length and angle at different time points (in a,b), P < 0.05: significant changes across the different time points over 24-h period. Underlying data for Fig 5 are available in S2 Data.

Fig 5

doi: https://doi.org/10.1371/journal.pbio.3003197.g005