Two distinct subpopulations of human stem-like memory T cells exhibit complementary roles in self-renewal and clonal longevity
Fig 4
CD95hi and CD95int frequencies differ between the blood and the lymph nodes.
PBMCs and lymph node cells isolated from the blood and axillary lymph nodes, respectively, of 7 healthy vaccinated volunteers from Cohort 3 were isolated and stained. Cells were gated on the population of (A) CD95int cells and (B) CD95hi cells. PBMC shown in red and lymph node cells in blue. Each dot represents one sample. CD95int TSCM (as a proportion of total TSCM) are significantly enriched in the LN, P = 0.029 unpaired two-tailed Wilcoxon test. Conversely CD95hi TSCM cells show a non-significant trend to be enriched in the blood P = 0.079. *P < 0.05. Bars represents the median, the box the interquartile range (IQR) and whiskers show lower quartile − 1.5 * IQR and upper quartile + 1.5 * IQR; all data points (including outliers) are shown by circles. The data underlying this figure can be found in S1 Data.