Oxytocin neurons drive melanocortin circuit maturation via vesicle release during a neonatal critical period
Fig 1
Close anatomical association between POMC and AgRP fibers and oxytocin neurons in the paraventricular nucleus.
(A, C). Representative images of OT (PS38) immunoreactive neurons and (A) POMC- and (C) AgRP-immunoreactive fibers in the paraventricular nucleus of the hypothalamus (PVH) of adult wild-type mice. (B, D). Quantification of the shortest distance between (B) POMC- or (D) AgRP-immunoreactive fibers and OT-immunoreactive cell bodies processes within the PVH (n = 5 animals per group). V3, third ventricle. Scale bar, 50 μm. The data underlying this Figure can be found in S1 Data.