Coordinated electrical activity in the olfactory bulb gates the oscillatory entrainment of entorhinal networks in neonatal mice
Fig 10
Schematic diagram of structural and functional coupling within OB–LEC networks of neonatal mice.
Mutual axonal projections (red) connect neonatal OB and LEC. Dotted line corresponds to weak anatomical connectivity. In OB of neonatal mice, continuous air flow–dependent RR and discontinuous MTC-driven theta bursts represent the two major patterns of oscillatory activity. They are augmented by olfactory stimuli (blue) that additionally evoke beta oscillations. OB activity boosts the oscillatory entrainment of neonatal LEC that, in turn, might drive the limbic circuits during development. HP, hippocampus; LEC, lateral entorhinal cortex; MTC, mitral and tufted cell; OB, olfactory bulb; PFC, prefrontal cortex; RR, respiration-related rhythm.