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Large-scale investigation of the reasons why potentially important genes are ignored

Fig 2

Features of genes and homologous genes predict discovery of human genes.

(A) Number of publications per gene for past and recent research. Publications of past research (until 2010) are scaled so that the total number of publications matches present research (2011–2015). Dashed grey lines delimit three standard deviations away from the mean. (B) Prediction of the number of research publications for the model of Fig 1A extended by including the year of the first publication on the specific human gene (S1 Data). (C) Prediction of the year of discovery using the features from Fig 1A (S1 Data). (D) Percentage of publications that cite publications with nonhuman genes more frequently than they cite publications with human genes (S1 Data). (E) Prediction of the year of initial publications on individual genes using the features from Fig 1A and the year of the initial publication on homologous genes of nonhuman model organisms (S1 Data). (F) Prediction of the number of research publications using the features of Fig 1A and the number of publications on homologous genes (S1 Data).

Fig 2

doi: https://doi.org/10.1371/journal.pbio.2006643.g002