The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials
Fig 2
Ethically sound informed consent requires disclosure of complete and accurate information about the potential risks and benefits of early trials.
Methodologically deficient preclinical studies preclude such adequate disclosures. This only compounds other well-documented problems in the informed consent process, resulting in potentially misinformed research participants.