Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondii
Fig 7
Phylogenetic profile of the alveolate infrakingdom for all T. gondii F-type ATP synthase subunits.
Alveolate clades are highlighted with a gray background, and their expected phylogenetic relationship is indicated by a tree structure above. Gray and white boxes indicate the presence and absence of the corresponding ortholog, respectively. The hatched boxes represent the presence of the ortholog in C. muris only and absence in C. parvum and C. hominis. The table on the left lists the gene ID for all ASAPs, along with their annotation, essentiality phenotypes (phenotype score from CRISPR/Cas9 knockout study [50]), and protein localization. The key for localization annotation is given below the table. ASAP, ATP synthase–associated protein; Cas9, CRISPR-associated 9; CRISPR, clustered regularly interspaced short palindromic repeat; OSCP, oligomycin sensitivity–conferring protein.