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Axonal Dynamics of Excitatory and Inhibitory Neurons in Somatosensory Cortex

Figure 9

Axons of inhibitory interneurons located within deprived rows following 2 d of whisker plucking.

(A) Left, axons located within deprived rows before plucking. Right, same area after 2 d of plucking. Axons that are stable over the two imaging sessions are color coded blue; those pruned after the first session colored red; and newly sprouted axons shown in yellow. (B–D) Quantification of changes in axonal length for 2 (B), 14 (C), and 30 (D) d of whisker plucking. As in Figure 8, the data are normalized relative to the highest density of retracted axons for each pair of time points. Retracted (left) and added (right) axons are plotted in 50 micron bins, with the injection site, shown by the asterisk, at coordinate (0,0,0). Distances are expressed in µm from injection site. The average locations of barrel columns for animals in each condition are marked on each graph. Deprived barrel column labels are in white, non-deprived barrel labels are in green.

Figure 9

doi: https://doi.org/10.1371/journal.pbio.1000395.g009