Axonal Dynamics of Excitatory and Inhibitory Neurons in Somatosensory Cortex
Figure 5
Changes in axonal density following varying durations of whisker plucking.
(A–D) For 2 (A), 14 (B), 30 (C), and 60 (D) d. Left column, first imaging session. Right column, second imaging session. The axonal length in each bin was averaged over multiple animals and then normalized. The normalization was performed by dividing all the bins in each baseline condition by the value of the highest density bin maximum in that condition. The bins in the corresponding post-plucking time point were divided by the same number. The maximum mean axonal length for any bin in each baseline graph is therefore 1.0 (expressed in arbitrary units, A.U.), and the length in the corresponding post-plucking graph is expressed relative to that standard. The bins in the histogram are 50 µm×50 µm; the injection site is located at coordinate (0,0,0). Average location of barrel column for animals in each condition is indicated on each graph. White text depicts deprived barrel columns. Green text depicts non-deprived barrel columns.