Brachyury expression levels predict lineage potential and axis-forming ability of in vitro-derived neuromesodermal progenitors

• Anahí Binagui-Casas ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: a.binagui-casas@ed.ac.uk (AB-C); v.wilson@ed.ac.uk (VW)

  ¶‡ These authors are joint first authors on this work.

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0002-7987-9286

  ⨯
• Anna Granés ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  ¶‡ These authors are joint first authors on this work.

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Alberto S. Ceccarelli ,

  Contributed equally to this work with: Alberto S. Ceccarelli, Matthew French

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

  Affiliation School of Biosciences, University of Nottingham, Sutton Bonington Campus, Nottingham, United Kingdom

  ⨯
• Matthew French ,

  Contributed equally to this work with: Alberto S. Ceccarelli, Matthew French

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

  Affiliation Department of Genetics, University of Cambridge, Cambridge, United Kingdom

  ⨯
• Filip J. Wymeersch,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Validation, Visualization, Writing – review & editing

  Affiliation RIKEN Center for Biosystems Dynamics Research, Kobe, Japan

  ⨯
• Rosa Portero Migueles,

  Roles Investigation

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Jennifer Annoh,

  Roles Investigation, Validation, Visualization

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Yali Huang,

  Roles Investigation

  Affiliation Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

  ⨯
• Eleni P. Karagianni,

  Roles Investigation

  Affiliation GSK, Stevenage, United Kingdom

  ⨯
• Frederick C. K. Wong,

  Roles Investigation, Writing – review & editing

  Affiliation The Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, United Kingdom

  ⨯
• Raffee Wright,

  Roles Investigation

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0002-2030-9035

  ⨯
• Anna Sophie Brumm,

  Roles Investigation

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Daniel Lopez Ramajo,

  Roles Investigation

  Affiliation Immunology Unit, Department of Pathology and Experimental Therapy, School of Medicine, Universitat de Barcelona, Barcelona, Spain

  ⨯
• Minoru Takasato,

  Roles Funding acquisition, Resources

  Affiliations RIKEN Center for Biosystems Dynamics Research, Kobe, Japan, Laboratory of Molecular Cell Biology and Development, Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

  ⨯
• Sally Lowell,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  ⨯
• Osvaldo Chara,

  Roles Data curation, Formal analysis, Funding acquisition, Methodology, Software, Supervision, Writing – review & editing

  Affiliations School of Biosciences, University of Nottingham, Sutton Bonington Campus, Nottingham, United Kingdom, Instituto de Tecnología, Universidad Argentina de la Empresa, Buenos Aires, Argentina

  ⨯
•  [ ... ],
• Valerie Wilson

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: a.binagui-casas@ed.ac.uk (AB-C); v.wilson@ed.ac.uk (VW)

  Affiliation Institute for Regeneration and Repair, Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

  https://orcid.org/0000-0003-4182-5159

  ⨯
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